Kanserde İmmünoterapi Yan Etkileri ve Yönetimi

İmmün kontrol noktası inhibitörleri olarak bilinen monoklonal antikorların onkoloji alanındaki etkinlikleri hergeçen gün daha iyi anlaşılmaktadır. Bu ilaçlar immün sistem üzerindeki inhibitör mekanizmaların engellenmesi yoluyla etkinlik göstermektedirler ve yan etkileri de aşırı immün yanıt sonucu ortaya çıkan otoimmün olaylar olarak tanımlanabilir. İmmün aracılı yan etkiler çok sık olmamakla beraber ilacın kesilmesi ve streoid kullanımı ile genellikle gerilemektedir. Dirençli vakalarda immünsüpresif tedaviler kullanılmaktadır.Bu ilaçlar ile olan deneyimlerin artması daha etkili tedavi algoritmaları geliştirilebilmesine ve yan etki profilinin daha iyi anlaşılabilmesine olanak sağlayacaktır

Side Effects and Management of Immunotherapy In Cancer

In oncology, the activity of monoclonal antibodies which known as immune checkpoint inhibitors is better understood every day. These drugs are efficaciousby inhibiting the inhibitory mechanisms in the immune system and their side effects can be defined as autoimmune events that caused by excessive immune response.. Immunerelated side effects are not very common and can usually be treated with steroids and dose modifications. Immunosuppressive treatments are used in resistant cases. Increasing the experience with these drugs will enable more effective treatment algorithms to be developed and a better understanding of the side effect profile

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Acıbadem Üniversitesi Sağlık Bilimleri Dergisi-Cover
  • ISSN: 1309-470X
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2010
  • Yayıncı: ACIBADEM MEHMET ALİ AYDINLAR ÜNİVERSİTESİ