Diyetin Mikrobiyotaya Etkisi ve Obeziteye Yansımaları

Dünya Sağlık Örgütünün DSÖ verilerine göre 1980 yılından bu yana iki kat artış gösteren obezite birçok sağlık sorununun gelişimine neden olmaktadır. Multifaktöriyel bir gelişimi olan obezite, temel olarak enerji alımının artması ve harcamanın azalmasının sonucunda ortaya çıkmaktadır. Enerji dengesinde önemli bir rol oynayan ve obezitenin oluşumunda etkisi oluğu düşünülen bir etmende bağırsak mikrobiyotasıdır. Beslenme alışkanlıklarının bağırsak mikrobiyotasını etkilediğini ve bağırsak mikrobiyomunun vücut ağırlığı üzerinde etkili olduğu bildirilmektedir. Bağırsak mikrobiyatasının enerji ekstraksiyonunu artırıp, immün sistem modülasyonunu ve lipid metabolizmasını değiştirerek konakçı metabolizmasını etkilediği düşünülmektedir. İnsan metabolizması üzerinde bu denli etkileri olan bağırsak mikrobiyotasının obezite ile ilişkisi üzerine yapılan çalışmalar, bağırsak mikrobiyotasının obezitenin önlenmesi ve tedavisinde etkili olabileceğini göstermektedir. Bu konunun öneminin ileri dönemlerde daha iyi anlaşılması için yapılan çalışmaların artması henüz tam olarak aydınlatılamayan konulara ışık tutması açısından önemlidir

The Effect of Diet On The Microbiota and Its Reflections On Obesity

Obesity which has increased by two folds since 1980 according to the data from the World Health Organization WHO leads to the development of many health problems. Obesity is a multifactorial disease, and fundamentally it develops due to increased energy intake and the reduction of energy expenditure in proportion to intake. One other factor that has an important role in energy balancing that is implicated in the development of obesity is the intestinal microbiota. It is being It has been reported that eating habits affect the intestinal microbiota and the intestinal microbiota affects the body weight. It is believed that the intestinal microbiota enhances energy extraction and affects the host metabolism by changing the modulation of the immune system and the lipid metabolism. Studies that are researching the relationship between obesity and the intestinal microbiota, which has such a great effect on the human metabolism, support the evidence idea that the intestinal microbiota could be effective in the prevention and treatment of obesity. Increasing the number of studies in this area is important to acquire a deeper understanding of this subject and to shed light on aspects still uncovered

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Acıbadem Üniversitesi Sağlık Bilimleri Dergisi-Cover
  • ISSN: 1309-470X
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2010
  • Yayıncı: ACIBADEM MEHMET ALİ AYDINLAR ÜNİVERSİTESİ