Duygu AYAZ, Sevil SAYHAN, Dudu SOLAKOĞLU KAHRAMAN, Volkan KARATAŞLI

Uterus Adenosarkomları: On Üç Olgunun Klinikopatolojik Değerlendirmesi

Uterus Adenosarkomları: 13 olgunun klinikopatolojik değerlendirmesi AMAÇ:Müllerian adenosarkomlar, çoğunlukla uterusta görülen, benign epitelial ve malign mezenkimal komponentten oluşan nadir bifazik tümörlerdir.Bu çalışmada uterus adenosarkomlarının klinik ve histopatolojik özelliklerini gözden geçirmeyi amaçladık. GeREÇ VE YÖNTEMLER:.Çalışmamızda, 1 Ocak 2009-1 Ocak 2020 tarihleri arasında tanı alan uterus adenosarkom olgularının klinik verileri tıbbi kayıtlar gözden geçirilerek elde edildi. Patoloji speysmenleri ise tekrar incelendi. BULGULAR: Hastanemizde tanı alan, tedavi takibi yapılan 13 uterin adenosarkom olgusunu çalışmaya dahil ettik.Tümörlerin tümünün endometriumdan köken aldığı izlenirken hastaların %69.2’si tanı anında 1. evredeydi. Hastaların %69.3’ünde evreleme yapıldı.Olguların %69.2’sinde mezenkimal komponenet yüksek dereceli olup tümünde sarkomatöz aşırı büyüme dikkati çekti.SONUÇ: Literatürle uyumlu olarak sarkomatöz aşırı büyüme, derin myometrial invazyon ve heterolog komponent varlığının, kısa sağkalım süreleriyle ilişkili olduğunu saptadık. Anahtar sözcükler: Müllerian adenosarkom, uterus, sarkomatöz aşırı büyüme Uterine Adenosarcoma: Clinicopathological evaluation of 13 cases OBJECTIVE: Mullerian adenosarcomas are rare biphasic tumors mostly seen in the uterus, consisting of benign epithelial and malignant mesenchymal components. In this study, we aimed to review the clinical and histopathological features of uterine adenosarcoma. MATERIAL AND METHODS: In our study, clinical data of ureus adenosarcoma cases diagnosed between 1 January 2009 and 1 January 2020 were obtained by reviewing medical records. Pathology speysmenelri were examined again. RESULTS. We included 13 uterine adenosarcoma cases diagnosed in our hospital and followed-up. While all tumors originated from the endometrium, 69.2% of the patients were in the first stage at the time of diagnosis. Staging was performed in 69.2% of patients. Mesenchymal component was high in 69.2% of cases, and sarcomatous overgrowth was noted in all. CONCLUSION: In accordance with the literature, we found that the presence of sarcomatous overgrowth, deep myometrial invasion and heterologous component was associated with short survival times. Keywords: Mullerian adenosarcoma, uterus, sarcomatous overgrowth

Anahtar Kelimeler:

, uterus, Müllerian adenosarkom, sarkomatoid aşırı büyüme

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