Serkan ÖZTÜRK, İsmail DOĞAN, Kayıhan KARAMAN, Alim ERDEM, Mehmet Fatih ÖZLÜ, Suzi Selim AYHAN, Mehmet YAZICI

Ortalama trombosit hacmi; akut ST elevasyonlu miyokard enfarktüsünde infarkt büyüklüğünün öngördürücüsü değildir

Amaç: Artmış ortalama trombosit hacmi ile akut koroner sendrom arasındaki ilişki bilinmektedir. Bu çalışmada ST elevasyonlu miyokard infarktüsü STEMI ile başvuran hastalarda sintigrafik olarak tespit edilen infarkt büyüklüğü ile ortalama trombosit hacmi arasındaki ilişkinin belirlenmesi amaçlanmıştır. Yöntem: : Akut ST elevasyonlu MI ile hastaneye kabul edilen ve hastane kayıtlarından SPECT analizi olan 54 hasta 31 adet Anterior MI, 23 adet İnferior MI çalışmaya dahil edildi. Hastaların başvuru anında ve 24, 48, 72 saat sonrasında periferik venöz kandan alınan serum örnekleri ile hemogram, serum kardiyak kreatin kinaz miyokardiyal band CK-MB ve troponin T cTnT düzeyleri laboratuar kayıtlarından elde edildi. Trombosit sayısı, ortalama trombosit hacmi ve kardiyak enzim düzeyleri kaydedildi. Miyokardiyal nekroz alanının büyüklüğü SPECT analizi ile hesaplandı. Bulgular: Pik CK-MB ve cTnT düzeyleri örnek alınan her üç gün için aynı sonuç geçerli olmak üzere sintigrafik infarkt alanı ile pozitif ilişkili iken, ortalama trombosit hacmi ile ilişkili bulunmadı P=0,021, P

Anahtar Kelimeler:

Ortalama Trombosit Hacmi, İnfarkt Alanı, Akut Koroner Sendrom.

Mean platelet volume could not predict infarct size in patients with acute ST elevation myocardial infarct

Background: Increased mean platelet volume has been shown to associate with acute coronary syndromes. Aim of this study, to investigate the relationship between scintigraphic infarct size and mean platelet volume after acute ST elevation myocardial infarction STEMI , which has not been studied with imaging tools. Method: Fifth-four patients with acute STEMI 31 patients with anterior and 23 patients with inferior were included in the study who were performed single photon emission computed tomography SPECT . In all cases, venous peripheral blood samples for hematologic and biochemical measurements were drawn. Platelet count, mean platelet volume, creatine kinase-myocardial band protein CKMB protein , and cardiac troponin cTnT were obtained at admission and daily during the first 72 h after a patient’s arrival by laboratory record. The severity scores of infarct size were calculated by SPECT. Results: Peak CKMB-protein, peak cTnT were positively correlated with, scintigraphic infarct size but mean platelet volume was not correlated with scintigraphic infarct size P=0,021, P

Keywords:

Mean Platelet Volume, Infarct Size, Acute Coronary Syndrome.,

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