Nihat ŞINDAK, Mustafa Barış AKGÜL, Ali GÜLAYDIN, Zelal KARAKOÇ

Japon Bıldırcınlarında (Coturnix Coturnix Japonica) Topikal Olarak Uygulanan Menengiç Yağı ve Farklı Deneysel Karışımlarının Yara İyileşmesi Üzerine Etkileri

Bu çalışmanın amacı; Japon bıldırcınlarında yara iyileşmesinde topikal kullanılan menengiç yağı ve farklı deneysel karışımlarının etkilerini araştırmaktır. Çalışmada hayvan materyalini 42 günlük, 30 adet ergin Japon bıldırcın oluşturdu. Her grupta 6 adet hayvan olacak şekilde 5 gruba ayrıldı. Her gruba bisturi ile yaklaşık 2 cm çapında deri ve deri altı bağ dokusunu kapsayan deneysel yara oluşturuldu ve hazırlanan karışımlar ile tedavi uygulandı. Yaralar günlük olarak izlendi ve pansuman değişimleri esnasında dijital kumpas yardımı ile ölçümü yapıldı. Yara oluşturulan günden sonra 3., 7., 10. ve 13. günlerde tüm gruplardan yara bölgesinden sağlam dokuyu da içine alacak şekilde biyopsi örnekleri alındı ve histopatolojik olarak incelendi. Araştırmada elde edilen veriler istatistiki olarak analiz edildi. En erken iyileşmenin şekillendiği grubun, grup II olduğu ve sırasıyla bunu grup I, grup III, grup IV ve kontrol grubunun takip ettiği saptandı. Histolojik değerlendirmelerde grup I ve grup II’ de diğer gruplara göre epitelizasyon sürecinin daha kısa sürede izlendiği saptandı. Çalışma sonucunda geleneksel olarak halk arasında kullanılan menengiç yağının ve %50 oranında Centella asiatica ekstratı içeren pomad karışımının bilimsel olarak bıldırcınlarda yara iyileşmesi üzerine olumlu etkilerinin olduğu kanaatine varıldı.

Anahtar Kelimeler:

Japon bıldırcını, Menengiç yağı, Nitrofurazon, Rifamisin, Centella asiatica

Effects of Topical Terebinth Berry Oil and Different Experimental Mixtures on Wound Healing in Japanese Quails (Coturnix Coturnix Japonica)

The aim of the presented study is to investigate the effects of terebinth oil and different experimental mixtures used topically in wound healing in Japanese quails. 42 days old 30 adult Japanese quail animals were used as live animal materials. The animals were divided into 5 groups each of containing 6 animals. Experimental scar involving skin and subcutaneous connective tissue of approximately 2 cm in diameter with each grubus scalpel was created and treated with the prepared mixtures. The injuries were monitored daily and measurements were made with digital calipers during dressing changes. On days 3th, 7th, 10th and 13th after the wound was created, biopsy specimens were taken from all groups to include intact tissue from the wound area and histopathologically examined. The data obtained were analyzed statistically. The group in which the earliest healing was formed was group II, followed by group I, group III, group IV and control group, respectively. Histological evaluations revealed that the epithelialization process was observed in group I and group II in a shorter time than the other groups. As a result of the study, it has been concluded scientifically that the mixture of menengic oil conventionally used by the public and pomade containing 50% Centella asiatica extract has positive effects on wound healing in quails.

Keywords:

Japanese quail, Terebinth berry oil, Nitrofurazone, Rifamisin, Centella asiatica,

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