Nihan UYGUR KÜLCÜ, Özlem ERDEDE, Mahmut DOĞRU, Gökçe Ezgi ERASLAN, Erdal SARI, Feyza YILDIZ

LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU

DRESS Sendromu (Drug Rush with Eosinophilia and Systemic Symptoms) ilaç ilişkili döküntü, hematolojik anormallikler (eozinofili, atipik lenfositoz), lenfadenopati, iç organ tutulumları (karaciğer, böbrek, akciğer) ile seyreden nadir, hayatı tehdit edebilen hipersensitivite reaksiyonudur. Antiepileptik lamotrigin tedavisi başlandıktan on dört gün sonra döküntüsü ve ateşi gelişen DRESS Sendromu olduğu düşünülen ergen bir kız hastayı sunduk.

Anahtar Kelimeler:

DRESS Sendromu, ilaç hipersensitivitesi, lamotrigine, çocuk

LAMOTRIGİNE INDUCED PROBABLE DRESS SYNDROME: CASE REPORT

Drug reaction with eosinophilia and systemic symptoms (DRESS Syndrome) is a rare, life-threatening, drug- induced hypersensitivity reaction that include skin eruptions, hematologic abnormalities (eosinophilia, atypical lymphocytosis), lymphadenopathy and internal organ involvement (liver, kidney, lung). We present an adolescent girl with probable DRESS Syndrome who had rash and fever after having been treated with lamotrigine as antiepileptic drug before fourteen days.

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