Nihan Uygur KÜLCÜ, Özlem ERDEDE, Mahmut DOĞRU, Gökçe Ezgi ERASLAN, Erdal SARI, Feyza Mediha YILDIZ

Lamotrigine Bağlı Olası Dress Sendromu: Olgu Sunumu

DRESS Sendromu (Drug Rush with Eosinophilia and Systemic Symptoms) ilaç ilişkili döküntü, hematolojik anormal-likler (eozinofili, atipik lenfositoz), lenfadenopati, iç organ tu-tulumları (karaciğer, böbrek, akciğer) ile seyreden nadir, hayatı tehdit edebilen hipersensitivite reaksiyonudur. Antiepileptik la-motrigin tedavisi başlandıktan on dört gün sonra döküntüsü ve ateşi gelişen DRESS Sendromu olduğu düşünülen ergen bir kız hastayı sunduk.

Lamotrıgine Induced Probable Dress Syndrome: Case Report

Drug reaction with eosinophilia and systemic symptoms (DRESS Syndrome) is a rare, life-threatening, drug- induced hypersensitivity reaction that include skin eruptions, hemato-logic abnormalities (eosinophilia, atypical lymphocytosis), ly-mphadenopathy and internal organ involvement (liver, kidney, lung). We present an adolescent girl with probable DRESS Sy-ndrome who had rash and fever after having been treated with lamotrigine as antiepileptic drug before fourteen days.

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