Şengül AYDIN YOLDEMİR, İsmet Çigdem KILIÇ

Gebelerde Tiroid Fonksiyon Testlerindeki Bozukluğun ve Erken Gebelikte Bakılan Hba1c Değerinin Gestasyonel Diyabet Mellitus Gelişimi ile İlişkisi

Amaç: Tiroid hastalıkları üreme çağındaki kadınları etkileyen en sık ikinci endokrin bozukluktur. Gestasyonel diyabet melli - tus(GDM) ise ilk kez gebelikte ortaya çıkan ya da gebelik sıra sında tanı konulan ve sıklığı günümüzde giderek artan glukoz tolerans bozukluğudur. Bu çalışma, erken gebelikte saptanan tiroid fonksiyon testleri bozukluğunun (TFTB) ve ilk trimesterde yapılan HbA1c ölçümlerinin, gebelikte ortaya çıkan GDM yi belirlemede önemli olup olmadığını araştırmak amacı ile yapılmıştır. Gereçler ve Yöntem: Çalışmada Merzifon Karamustafa Paşa Devlet Hastanesi İç Hastalıkları ve Kadın Doğum kliniklerine başvuran gebelik yaşı 6-20 hafta arasında değişen 82 gebe retrospektif olarak değerlendirildi. Gebelerin TSH, sT4, sT3, AKŞ, HbA1c değerleri ve GDM gelişimi tarandı. Çalışmada istatis tiksel analizler SPSS 15.0 programı kullanılarak yapıldı. P de - ğerinin

Relationship of Development of Gestational Diabetes Mellitus Between HbA1c Valide and Abnormal Thyroid Function Tests in Pregnant Women

Objective: Thyroid disease is the second most common endoc rine disease to affct women of reproductive age. Gestational Diabetes Mellitus is defined as glucose intolerance that comes out or is first recognized during pregnancy, and disappears after delivery. And the incidence is increasing. Thyroid function tests disorder and high HbA1c value which detected in early pregnancy, that the whether there is a risk factors for develo ping GDM in later stages of pregnancy. Material and Methods: Eighty-two women in weeks 6-20 of pregnancy attending the internal medicine clinics and the Obs tetrics and Gynaecology Clinics of Merzifon Karamustafa Paşa Government Hospital between January 2013 and July 2013 were investigated retrospectively in this study. Serum levels of TSH, fT4, fT3, FBG, HbA1c and development of GDM were assessed in all cases. Statistical analyzes were performed using SPSS 15.0 software. P values 6 in first trimester were found to be in higher risk for developing impaired glucose tole rance and gestational DM (p=0.03). Conclusion: Thyroid gland disfunction and high HbA1c levels in early pregnancy can be evaluated as risk factors in develo ping GDM. Thus,we suggest that these patients should be scre ened carefully during pregnancy

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