Nurdan Berna ŞENER, Fezan ŞAHİN

Çocuklardaki demir eksikliği anemisi'nde $Fe^{++}$ tedavisine C vitamini ilavesinin laboratuar cevabı üzerindeki etkileri

Amaç: Çocuklardaki Fe eksikliği anemisinde önerilen 2 değerlikli demir preparatlarına C vitamini eklenmesinin sadece $Fe^{++}$ alan gruba göre anemiyi düzeltmedeki etkinliğini saptamak Materyal ve Metod: Zeynep Kamil Kadın Hastalıkları ve Çocuk Hastanesi Çocuk Hastalıkları Polikliniği'ne başvuran çocuklar 2 gruba ayrılarak 1. gruba sadece $Fe^{++}$ , diğer gruba $Fe^{++}$ ve C vitamini başlanarak hematolojik parametreler 1. ay ve 2. ay sonunda değerlendirildi. Bulgular: Kontrol ve çalışma grupları arasında, hemoglobin (p>0.05), hematokrit (p>0.05), MCV (p>0.05), MCHC (p>0.05), MCH (p>0.05), KDW (p>0.05),$Fe^{++}$ (p>0.05), Fe bağlama (p>0.05), Ferritin (p>0.05), Transferrin saturasyonu (p>0.05)ve lökosit (p>0,05) açısından fark bulunmamıştır. Sonuç: Anemi tedavisi alan çocuklarda Ferröz demire ($Fe^{++}$) C vitamin eklenmesinin hematolojik parametrelerin iyileşmesine katkı sağlamadığı saptanmıştır.

Anahtar Kelimeler:

Anemi, demir eksikliği, Demir, Askorbik asit, Çocuk

Impact of vitamin C addition to $Fe^{++}$ supplementation in laboratory response in iron deficiency anemia of childhood

Objective: To evaluate the effect of adding Vitamine C to $Fe^{++}$ in treatment of iron deficiency anemia in childhood. Materials and Methods: Infants who applied to outpatient clinic of Zeynep Kamil Maternity Hospital and get the diagnosis of iron deficiency anemia were divided into two groups. First group received only $Fe^{++}$, second group received Vitamine C and $Fe^{++}$. Hematological results were evaluated at the end of first and second month. Results: Hemoglobine (p>0.05), hematocrite (p>0.05), MCV (p>0.05), MCHC (p>0.05), MCH (p>0.05), RDW (p>0.05),$Fe^{++}$ (p>0.05), Fe binding capacity (p>0.05), Ferritin (p>0.05), Fe saturation (p>0.05) and leucocyte levels (p>0.05) were similar in the groups. Conclusion: Adding Vitamin C to ferrous iron had no impact on hematological values in anemic children.

Keywords:

Anemia, Iron-Deficiency, Iron, Ascorbic Acid, Child,

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