Comparison of serum c-reactive protein levels between benign prostate hyperplasia and prostate cancer in patients undergoing prostate biopsy

Prostat kanserinin inflamasyonla ilişkisi olabileceği düşünülmektedir. Prostat spesifik antijen prostat kanserinin tanı, tedavi ve takiplerde yaygın olarak kullanılmaktadır. C-reaktif protein inflamasyonda yaygın kullanılan bir belirteçtir. Çalışmamızda tPSA'sı >4,0 ng/ml olan ve biyopsi yapılmış hastalarda biyopsi sonucu benign prostat hiperplazisi (BPH) ve prostat kanseri (PCa) gelenler arasındaki serum CRP değerlerini karşılaştırdık. Gereç ve Yöntemler: tPSA >4,0 ng/dl olan ve biyopsiye karar verilen 182 hastada serum CRP ve sedimentasyon hızlarına bakıldı. Retrospektif değerlendirme yapıldı. 175 hastanın patolojik verilerine ulaşıldı. BPH ve PCa arasındaki CRP'ler Wilcoxon-Mann Whitney U ve Kruskal Wallis testleri yöntemleriyle çalışılarak karşılaştırıldı. İstatisiksel değerlendirmede p

Prostat biyopsisi uygulanan hastalarda serum c-reaktif protein düzeylerinin benign prostat hiperplazisi ve prostat kanseri arasında karşılaştırılması

It has been argued that prostate cancer may have an association with inflammation. Prostate specific antigen is widely used for diagnosis, treatment, and follow-up of prostate cancer. C-reactive protein is a widely utilized marker of inflammation. We compared serum CRP values between benign prostate hyperplasia (BPH) and pılmış hastalarda biyopsi sonucu benign prostat hiprostate cancer (PCa) diagnosed by prostate biopperplazisi (BPH) ve prostat kanseri (PCa) gelenler sy performed in patients with a tPSA level greater than 4.0 ng/dl. Material and Methods: Serum CRP and sedimentation rate were retrospectively assessed in 182 patients who had a tPSA level above 4.0 ng/dl and were scheduled to undergo prostate biopsy. Pathology results of 175 patients could be accessed. CRP levels of patients with BPH and PCa were testleri yöntemleriyle çalışılarak karşılaştırıldı. İscompared with each other using Wilcoxon-Mann tatisiksel değerlendirmede p<0.05 değeri anlamlılık Whitney U and Kruskal Wallis tests. A p value of less than 0.05 was considered statistically significant. Results: Both the analyses taking a CRP cutoff level of 0.5 mg/dl and quantitative serum CRP levels failed to show any significant difference between the BPH group (0.59+0.11 mg/dl) and the PCa group (0.55+0.18 mg/dl) (p=0.779; p=0.192). Sedimentation rate was also similar in the BPH ğerleri (18,98 mm/saat) ile PCa sedimentasyon hızı and PCa groups (18.98 mm/hour vs 18.18 mm/değerleri (18,18 mm/saat) birbirine benzerdi, aralahour; p=0.870).Conclusion: Our study could not demonstrate any significant difference between serum nın arasında serum CRP değerleri arasında anlamlı CRP levels of patients with BPH and PCa.fark bulunamadı

Kaynakça

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Kaynak Göster

Yeni Üroloji Dergisi
  • ISSN: 1305-2489
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2005

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