Mehmet Nuri BODAKÇI, Namık Kemal HATİPOĞLU, Necmettin PENBEGÜL, Murat ATAR, Mansur DAĞGÜLLİ, Hüsamettin ERDAMAR

Akut skrotum tanısında prokalsitonin değeri

Amaç: Bu prospektif çalışmanın amacı akut skrotumun ayrıcı tanısında akut faz proteinleri, prokalsitonin ve antioksidan enzimlerin önemini belirlemektir.Yöntem ve Gereçler: Çalışmaya akut skrotumu olan 23 hasta Grup 1 epididimit n=17, testis torsiyonu n=6 ve aynı yaş grubundan 23 sağlıklı erkek Grup 2 dâhil edildi. Tüm hastaların ve kontrol grubunun kan ve serumları beyaz küre WBC , albumin, nötrofil oranı, C-reaktif protein CRP , eritrosit sedimentasyon hızı ESR , süperoksit dismutaz SOD , katalaz CAT , glutatyon peroksidaz GPX ve prokalsitonin açısından değerlendirildi. Sonuçlar klinik bulgular, rutin kan ve idrar tetkikleri ve doppler ultrasonografi ile kontrol edildi.Bulgular: Tüm hastaların ortalama yaşı 30.17±12.46 yıl iken grup 1 de 29,96±15,85 ve grup 2 de 30,40±7,21 yıl idi. Bütün hastalarda şikayetin başlamasından hastaneye müracaat ettikleri zamana kadar geçen süre ortalama 89,6 saat iken, epididimoorşit olan hastalarda bu süre 100 saat ve testis torsiyonu olanlarda ise 42 saat olarak tespit edildi. Ek olarak testis torsiyonu tanısı konulan hastalardan sadece 1 tanesi 18 yaşından büyük iken 42 yaş epididimo-orşit tanısı alan hastaların 8 tanesi 18 yaşından küçüktü. Grup 1 ve grup 2 sonuçları karşılaştırıldığında WBC, nötrofil oranı, albumin, ESR, CRP, SOD, CAT ve GPX değerleri grup1’de istatiksel olarak anlamlı derecede yüksek idi. Ancak testis torsiyonu olan hastalarda, sadece prokalsitonin hem epididimoorşit olan hastalardan hem de kontrol grubundan istatiksel olarak anlamlı derecede yüksek bulundu p0.05 . Sonuç: Akut faz proteinleri özellikle prokalsitonin akut skrotumun ayırıcı tanısında testis torsiyonunu epididimin diğer enflamatuar hastalıklarından ayırt etmede kullanılabilir

Anahtar Kelimeler:

Akut skrotum, testis torsiyonu, prokalsitonin

The value of procalcitonin in the diagnosis of acute scrotum

Objectives: In a prospective study, we investigated the value of acute-phase proteins, procalcitonin and anti-oxidant enzymes in differential diagnosis of acute scrotum. Material and Methods: A total of 23 patients epididymitis n=17, testicular torsion n=6 with acute scrotum Group 1 and 23 healthy men as a control group Group 2 were included in the study. All patients were assessed by blood analysis for serum levels of white blood cells WBC , albumin, neutrophil rate, C-reactive protein CRP , eritrosit sediment rate ESR , superoxide dismutase SOD , catalase CAT , glutathione peroxidase GPX , and procalcitonin. The results were confirmed by the clinical findings, routine blood and urine tests and Doppler ultrasound. Results: The mean age of all patients was 30.17±12.46; while the mean ages of each group were 29,96±15,85 and 30,40±7,21 respectively. Mean time from the beginning of patient complaint to admission to hospital was 89.6 hours range: 10-240 hours in the patient group whereas the time was 100 hours in epididymo-orchitis patients and 42 hours in spermatic cord torsion. In addition, 1 patient 4.3% with torsion was over 18 years old 42 years old , while 8 with acute epididymitis were younger than 18 years old. When group 1 was compared with group 2, WBC, neutrophil albumin, sedimentation, CRP, SOD, CAT and GPX were statistically higher in group 1. However, only procalcitonin was higher when compared with torsion and epididymo-orchitis patients and also higher than group 2 p

Keywords:

Acute scrotum, testes torsion, procalcitonin,

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