İsmail DEMİRCİOĞLU, Yasin DEMİRASLAN, İftar GÜRBÜZ, Orhun DAYAN

Yeni Zelanda Tavşanlarında Hipofiz Bezi’nin (Gandula pituitaria) Topografisi ve Morfometrisinin Bilgisayarlı Tomografi ile İncelenmesi

Çalışmada, Yeni Zelanda tavşanında hipopysis’in bilgisayarlı tomografi görüntüleri kullanılarak, morfometrisinin ve cavum cranii’deki anatomik yapılara göre topografisinin belirlenmesi amaçlandı. Bu amaçla çalışmada 12 adet (6 dişi, 6 erkek) Yeni Zelanda tavşanının, cranium bölgesi, prone pozisyonda, Multi Detector Computed Tomography kullanılarak, 0,625 mm kesit kalınlığında tarandı. Elde edilen görüntülerin üç boyutlu modellemeleri yapıldı. Üç boyutlu modellemeleri yapılan hipophysis bezinin morfometrik analizi ve komşuluğu bulunan yapılara göre topografik ölçümleri alındı. Veriler incelendiğinde protuberantia occipitalis externa değerinin cinsiyetler açısından istatistiki olarak anlamlı olduğu belirlendi (P<0.05). Diğer veriler arasında cinsiyetler arasında istatistiki olarak anlamlı bir fark belirlenmedi (P>0.05). Korelasyon analizi incelendiğinde ise, bez hacmi ile cavum cranii hacmi arasında (P<0.01) ve cavum cranii hacmi ile cavum cranii yüzey alanı arasında (P<0.05) pozitif korelasyonlar tespit edildi. Sonuç olarak çalışma verilerinin, Hypophysis bezinin Yeni Zelanda tavşanlarındaki morfometresini ve topografisini belirleyerek bölge üzerinde yapılacak operatif ve deneysel çalışmalara katkı sağlayacağı düşünülmektedir.

Anahtar Kelimeler:

Hipofiz, gl. pituitaria, topografi, Yeni Zelanda tavşanı

Examination of the Topography and Morphometry of Hypophysis (Glandula pituitaria) by Computed Tomography in New Zealand Rabbits

The aim of this study is to determine the morphometry of hypophysis of the New Zealand rabbit by using the computed tomography images and its topography according to the anatomical structures in the cavum cranii. For this purpose, the head of 12 (6 female, 6 male) New Zealand Rabbits was scanned in a prone position by using Multi-Detector Computed Tomography. Three-dimensional modeling of the images obtained was performed. Morphometric analysis of the hypophysis, the three-dimensional modeling of which was performed, and its topographic measurements were taken according to the adjacent structures. When the data were examined, it was found that protuberantia occipitalis externa value was statistically significant in terms of sexes (P<0.05). There was no statistically significant difference between other data in terms of sexes (P>0.05). When the correlation analysis was examined, positive correlations between the gland volume and volume of cavum cranii (P<0.01) and between volume and surface area of cavum cranii were detected (P<0.05). Consequently, it is thought that the data of the study would contribute to the operative and experimental studies to be conducted on the region by determining the morphometry and topography of the hypophysis in New Zealand rabbits.

Keywords:

Gl. pituitaria, hypophysis, New Zealand rabbit, topography,

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