İsmet HORTU, Şevki ÇETİNKALP, Mehmet ERDOĞAN, Aslı SUNER, Ahmet Mete ERGENOĞLU, Hatice ÖZIŞIK

Gestasyonel Diyabetli ve Gestasyonel Diyabet Olmayan Gebelerde Tiroid Fonksiyon Testlerinin Karşılaştırılması

Amaç: Bu çalışmanın amacı, gestasyonel diyabeti olan ve olmayan gebelerde tiroid hormon düzeylerinde ve anti-tiroid peroksidaz antikorlarında farklılık olup olmadığını belirlemektir. Gereç ve Yöntemler: 107 gebe kadının tıbbi kayıtlarını incelendi. Anne yaşı, gebelik haftası, vücut kütle indeksi, tiroid fonksiyon testleri ve antitiroid peroksidaz antikorları, açlık kan şekeri testleri ve HbA1c düzeyleri ile ilgili klinik veriler elde edildi. Pearson ki-kare testi, Mann-Whitney U testi ve bağımsız örnekler t testi, Spearman korelasyon katsayısı ve lojistik regresyon modeli uygulandı Bulgular: Gestasyonel diyabet grubu anlamlı olarak daha yaşlıydı (p=0,001). Vücut kütle indeksi iki grup arasında istatistiksel olarak farklıydı (p=0,002). İki grup arasında açlık kan şekeri ve HbA1c açısından istatistiksel olarak anlamlı farklılıklar vardı (sırasıyla p

Anahtar Kelimeler:

gestasyonel diyabet, hipotiroidizm, anti tiroid peroksidaz antikorları

Comparison of Thyroid Function Tests in Pregnant Women with and without Gestational Diabetes

Aim: The aim of this study was to determine whether there were abnormalities in thyroid hormone levels and anti-thyroid peroxidase antibodies in pregnant women with and without gestational diabetes mellitus. Material and Methods: We analyzed the medical records of 107 pregnant women. Clinical data related to maternal age, gestational week, body mass index, thyroid function tests, and anti-thyroid peroxidase antibodies, fasting blood glucose tests and HbA1c levels were obtained. The Pearson chi-square test, the Mann-Whitney U test, independent samples t-test, the Spearman correlation coefficient and Logistic regression model were performed. Results: Gestational diabetes mellitus group was significantly older (p=0.001). Body mass index was statistically different between the two groups (p=0.002). There were statistically significant differences in fasting blood glucose and HbA1c between the two groups (p

Keywords:

Gestational diabetes mellitus, Hypothyroidism, Anti-thyroid peroxidase antibodies,

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