Tuğba RAMASLI GÜRSOY, Tuğba ŞİŞMANLAR EYÜBOĞLU, Ayşe Tana ASLAN, Ramazan KARABULUT, Abdullah TAŞTEPE

Prenatal ve Postnatal Dönemde Tanı Alan Konjenital Akciğer Malformasyonu Olan Çocukların Değerlendirilmesi

Amaç: Çalışmamızda prenatal ve postnatal dönemde tanı alan konjenital akciğer malformasyonu olan hastaların klinik özelliklerini karşılaştırmayı amaçladık. Gereç ve Yöntemler: 2007-2021 yılları arasında Çocuk Göğüs Hastalıkları Bölümü’nde izlenen konjenital akciğer malformasyonu olan hastalar cinsiyetleri, yaşları, başvuru yakınmaları, ilk semptom zamanı, tanı yaşları, tanı yöntemleri, doğum haftaları, doğum ağırlıkları, ebeveyn akrabalığı, operasyon varlığı, operasyon yaşı ve endikasyonları, uzun dönem komplikasyonları açısından değerlendirildi. Prenatal dönemde tanı alan hastalar ile postnatal dönemde tanı alanlar klinik özellikleri açısından karşılaştırıldı. Bulgular: Konjenital akciğer malformasyonu nedeniyle izlenen 37 hastanın ortalama yaşları 6.7±5.8 yıldı ve 17’si (%45.9) kızdı. Prenatal dönemde tanı alan hastalar (n:18) yakınması olmadan başvururken diğer hastaların en sık başvuru nedenleri öksürük ve tekrarlayan akciğer enfeksiyonuydu. Postnatal dönemde tanı alan hastaların (n:19) ortanca tanı yaşları 30 (en küçük:10; en büyük:1080) gündü. Hastaların 18’i (%48.6) prenatal ultrasonografi, 14’ü (%37.8) bilgisayarlı tomografi, beşi (%13.6) akciğer grafisi ile tanı aldı. İzlemde iki hastanın malformasyonu kendiliğinden geriledi. Oniki hasta opere olurken diğer hastalar mevcut anomalileri ile takip edilmektedir. Prenatal dönemde tanı alan hastaların asemptomatik izlem süresi, postnatal tanı alan hastalardan istatistiksel olarak anlamlı farklıydı (36.5±4.7 ve 24.0±12.7 ay) (p:0.004). Sonuç: Çalışmamızda prenatal dönemde tanı alan konjenital akciğer malformasyonu olan hastaların daha uzun süre

Anahtar Kelimeler:

Çocuk, konjenital akciğer malformasyonu, prenatal tanı

Evaluation of Children with Congenital Lung Malformations Who Were Diagnosed in The Prenatal and Postnatal Period

Objective: We aimed to compare clinical features of children with congenital lung malformations (CLM) who were diagnosed in prenatal and postnatal period. Material and Methods: Children with CLM followed in our pediatric pulmonology department between 2007-2021 were evaluated in terms of sex, age, complaints at presentation, time of onset of symptoms, age at diagnosis, diagnostic methods, gestational ages, birth weights, parental consanguinity, presence of any operations, age and indications of operations and long-term complications. Children who were diagnosed in prenatal period and those in postnatal period were compared in terms of their clinical features. Results: The mean age of 37 children with CLM was 6.7±5.8 years, and seventeen (45.9%) of the children were girls. Children who were diagnosed during the prenatal period (n:18) had no complaints, whereas cough and recurrent pneumonia were the most common reasons at admission in others. Median age at diagnosis of children who were postnatally diagnosed (n:19) was 30 days (10-1080). Eighteen (48.6%) children were diagnosed by prenatal ultrasonography, 14 (37.8%) by computed tomography, and five (13.6%) by chest X-ray. During follow-up, malformations of two children regressed spontaneously. Twelve children were operated while others were followed up with their anomalies. Asymptomatic follow-up duration of children who were prenatally diagnosed was significantly different than the children who were diagnosed in the postnatal period (36.5±4.7 vs 24.0±12.7 months) (p:0.004). Conclusion: Children with CLM who were diagnosed in the prenatal period were found to remain asymptomatic for longer. Prenatal diagnosis enables them to live longer without symptoms with appropriate surgical timing.

Keywords:

Child, congenital lung malformations, prenatal diagnosis,

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