Gastroözofagiel Reflü Hastalığı Olan Çocuk ve Adolesanlarda Yaşam Kalitesi

Amaç: Gastroözofageal reflü hastalığı (GÖRH) olan çocukluklarda önemli komorbidite vardır. Bu çalışmada, hasta çocuk ve ergenlerin sağlıkla ilgili yaşam kalitesini (SYK) hastanın kendisi ve ebeveynlerin doldurduğu anketlerle değerlendirmeyi amaçladık. Ek olarak, gastroözofageal reflü semptomlarının SYK üzerindeki etkisi de araştırıldı. Gereç ve Yöntemler: Çalışmaya 93 hasta ve 59 yaş ve cinsiyet uyumlu sağlıklı kontrol dahil edildi. Yüzyüze görüşmeyle çocuklardan ve ebeveynlerinden çocuğun SYK’ni değerlendirmek için Türkçe geçerli ve güvenilir versiyonu olan KINDer Lebensqualitätsfragebogen-Çocuk Yaşam Kalitesi Anketi’ni doldurmaları istendi. Hastalar ayrıca bir gastroözofageal reflü semptom anketi de doldurdular. Bulgular: Hastaların ve ebeveynlerinin SYK puanı sağlıklı kontrollere göre anlamlı olarak daha düşük bulundu (p=0.004). Özellikle bedensel iyilik ve duygusal iyilik alt ölçekleri olumsuz etkilenmişti (sırasıyla p=0.000 ve p=0.002). Hastalarda en sık görülen semptomlar epigastrik ağrı (%70.9), karında şişkinlik (%64.5), ağız kokusu (%58) ve regurjitasyon (%50.6)’di. Epigastrik ağrı hastalarda toplam SYK’ni anlamlı olarak olumsuz etkiledi (p= 0.003). Hastalarla ebeveynlerinin doldurduğu anketler karşılaştırıldığında hasta çocukların bedensel iyilik (p=0.000) ve aile (p=0.000) alt ölçek puanları ebeveynlerine göre anlamlı derecede yüksekti. GÖRH olan hastalar, öz saygı (p=0.000) ve okul alanlarındaki yaşam kalitesini (p=0.001) ebeveynlerine göre daha olumsuz olarak değerlendirdi. Sonuç: GÖRH, çocuklarda SYK üzerinde önemli bir olumsuz etkiye sahiptir. En çok etkilenen alanlar bedensel iyilik ve duygusal iyilik halidir. Epigastrik ağrı, daha kötü SYK skorları ile ilişkilidir.

Anahtar Kelimeler:

Yaşam kalitesi, Çocuk, Gastroözofagiel reflü hastalığı

Quality of Life in Children and Adolescents with Gastroesophageal Reflux Disease

Objective: Children with gastroesophageal reflux disease (GERD) have significant co-morbidity. This study aimed to evaluate the health-related quality of life (HRQoL) in these children and adolescents by self and parent questionnaires. In addition, we also investigated the impact of gastroesophageal reflux symptoms on HRQoL. Material and Methods: The study included 93 patients with GERD and 59 age and sex-matched healthy controls. We asked the children and their parents to complete the validated Turkish version of KINDer Lebensqualitätsfragebogen-Children Quality of Life Questionnaire (self-report and parent report, respectively) for assessing HRQoL. The patients have additionally completed a gastroesophageal reflux symptom questionnaire. Results: The patients and their parents scored significantly lower on the general health perception (p=0.004) than the healthy controls. Especially physical well-being and emotional well-being subscales were negatively affected (p=0.000, and p=0.002, respectively). The most common symptoms in the patients were epigastric pain (70.9%), abdominal distention (64.5%), halitosis (58%), and regurgitation (50.6%). Epigastric pain significantly negatively affected the total HRQoL score in the patients (p= 0.003). The patients with GERD scored significantly higher than their parents in physical well-being (p=0.000) and family (p=0.000) subscale scores. The patients with GERD evaluated their quality of life more negatively in self-esteem (p=0.000) and school domains (p=0.001) than did their parents. Conclusion: GERD has a significant negative impact on HRQoL in children. The most affected domains are physical well-being and emotional well-being. Epigastric pain is associated with worse HRQoL scores.

Keywords:

Child, Gastroesophageal reflux, Quality of life,

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