The use of proligestone, megestrol acetate and GnRH on queens with the aim of hormonal contraception

The aim of this study was to investigate the efficacy of the use of two different progestagens either singly or in a combination with GnRH on queen contraception. The study was performed on a total of 73 female cats of various breeds at various stages of cycles. Queens at interoestrous (n=35) and oestrous periods (n=38) of sexual activity were treated under two main groups. Twenty cats of the first main group at interoestrous period (Group-1/A) were administered 30 mg/kg (sc) proligestone (PRG) and the remaining 15 cats (Group-1/B) were administered 25 mg (sc) megestrol acetate (MA). The cats at oestrous period were first given 50 mg gonadotropin releasing hormone (GnRH) (im). 48-96 hours following the application 23 of these cats (Group-2/A) were administered 30 mg/kg (sc) PRG, while the other 15 cats (Group-2/B) were administered 25 mg (sc) MA. The disappearance of oestrous symptoms was established to be 2.85±0.74 days in Group-1/A, 2.93±1.35 days in Group1/B, 3.08±0.84 days in Group-2/A and 2.86±0.64 days in Group-2/B. Following hormonal injection the periods of remaining calm were established to be 8.00±2.20 months in Group-1/A, 3.33±1.01 months in Group-1/B, 7.57±2.35 months in Group-2/A and 4.90±2.65 months in Group-2/B. No difference has been established among mean values from the point of view of the disappearance of oestrous symptoms among groups (Group-1/A:Group-1/B= p

The use of proligestone, megestrol acetate and GnRH on queens with the aim of hormonal contraception

The aim of this study was to investigate the efficacy of the use of two different progestagens either singly or in a combination with GnRH on queen contraception. The study was performed on a total of 73 female cats of various breeds at various stages of cycles. Queens at interoestrous (n=35) and oestrous periods (n=38) of sexual activity were treated under two main groups. Twenty cats of the first main group at interoestrous period (Group-1/A) were administered 30 mg/kg (sc) proligestone (PRG) and the remaining 15 cats (Group-1/B) were administered 25 mg (sc) megestrol acetate (MA). The cats at oestrous period were first given 50 mg gonadotropin releasing hormone (GnRH) (im). 48-96 hours following the application 23 of these cats (Group-2/A) were administered 30 mg/kg (sc) PRG, while the other 15 cats (Group-2/B) were administered 25 mg (sc) MA. The disappearance of oestrous symptoms was established to be 2.85±0.74 days in Group-1/A, 2.93±1.35 days in Group1/B, 3.08±0.84 days in Group-2/A and 2.86±0.64 days in Group-2/B. Following hormonal injection the periods of remaining calm were established to be 8.00±2.20 months in Group-1/A, 3.33±1.01 months in Group-1/B, 7.57±2.35 months in Group-2/A and 4.90±2.65 months in Group-2/B. No difference has been established among mean values from the point of view of the disappearance of oestrous symptoms among groups (Group-1/A:Group-1/B= p
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK