Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)

The plasma concentration of long-acting oxytetracycline (OTC-LA) was measured following a single intramuscular (IM) injection (50 mg/kg) in grouper (Epinephelus marginatus), a common inhabitant of marine aquaria and a potential candidate for fish farming. The experiment was carried out at 20 °C and sampling points were selected at 0.25, 0.5, 1, 2, 4, 6, 8, 12, 24, and 48 h post-administration. OTC concentration in grouper circulation was maintained at high levels for the whole experiment (8.35-39.67 mg/mL) with maximum plasma concentration measured at 1 h post-injection. The area under the curve values was also promising since AUC0-24 and AUC 0-48 were calculated to be high (363.45 and 668.73 mg h/mL, respectively). Due to the high OTC levels accomplished for prolonged period of time, a single administration of OTC-LA could be an ideal route in cases when multiple handling is unwanted and big animals such as grouper are to be treated.

Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)

The plasma concentration of long-acting oxytetracycline (OTC-LA) was measured following a single intramuscular (IM) injection (50 mg/kg) in grouper (Epinephelus marginatus), a common inhabitant of marine aquaria and a potential candidate for fish farming. The experiment was carried out at 20 °C and sampling points were selected at 0.25, 0.5, 1, 2, 4, 6, 8, 12, 24, and 48 h post-administration. OTC concentration in grouper circulation was maintained at high levels for the whole experiment (8.35-39.67 mg/mL) with maximum plasma concentration measured at 1 h post-injection. The area under the curve values was also promising since AUC0-24 and AUC 0-48 were calculated to be high (363.45 and 668.73 mg h/mL, respectively). Due to the high OTC levels accomplished for prolonged period of time, a single administration of OTC-LA could be an ideal route in cases when multiple handling is unwanted and big animals such as grouper are to be treated.

___

Bibtex @ { tbtkveterinary150835, journal = {Turkish Journal of Veterinary and Animal Sciences}, issn = {1300-0128}, eissn = {1303-6181}, address = {}, publisher = {TÜBİTAK}, year = {2010}, volume = {34}, pages = {441 - 445}, doi = {}, title = {Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)}, key = {cite}, author = {Rıgos, George and Katharıos, Pantelis and Papandroulakıs, Nikos} }
APA Rıgos, G , Katharıos, P , Papandroulakıs, N . (2010). Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus) . Turkish Journal of Veterinary and Animal Sciences , 34 (5) , 441-445 .
MLA Rıgos, G , Katharıos, P , Papandroulakıs, N . "Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)" . Turkish Journal of Veterinary and Animal Sciences 34 (2010 ): 441-445 <
Chicago Rıgos, G , Katharıos, P , Papandroulakıs, N . "Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)". Turkish Journal of Veterinary and Animal Sciences 34 (2010 ): 441-445
RIS TY - JOUR T1 - Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus) AU - George Rıgos , Pantelis Katharıos , Nikos Papandroulakıs Y1 - 2010 PY - 2010 N1 - DO - T2 - Turkish Journal of Veterinary and Animal Sciences JF - Journal JO - JOR SP - 441 EP - 445 VL - 34 IS - 5 SN - 1300-0128-1303-6181 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Veterinary and Animal Sciences Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus) %A George Rıgos , Pantelis Katharıos , Nikos Papandroulakıs %T Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus) %D 2010 %J Turkish Journal of Veterinary and Animal Sciences %P 1300-0128-1303-6181 %V 34 %N 5 %R %U
ISNAD Rıgos, George , Katharıos, Pantelis , Papandroulakıs, Nikos . "Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)". Turkish Journal of Veterinary and Animal Sciences 34 / 5 (Mayıs 2010): 441-445 .
AMA Rıgos G , Katharıos P , Papandroulakıs N . Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus). Turkish Journal of Veterinary and Animal Sciences. 2010; 34(5): 441-445.
Vancouver Rıgos G , Katharıos P , Papandroulakıs N . Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus). Turkish Journal of Veterinary and Animal Sciences. 2010; 34(5): 441-445.
IEEE G. Rıgos , P. Katharıos ve N. Papandroulakıs , "Single intramuscular administration of long-acting oxytetracycline in grouper (Epinephelus marginatus)", Turkish Journal of Veterinary and Animal Sciences, c. 34, sayı. 5, ss. 441-445, May. 2010
Turkish Journal of Veterinary and Animal Sciences
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

61.6b55.9b