İhsan KELEŞ, Süleyman KOZAT, Nazmi YÜKSEK, Yaşar GÖZ

Serum iron, total iron-binding capacity, unbound iron-binding capacity, transferrin saturation, serum copper, and hematological parameters in pregnant Akkaraman ewes infected with gastro-intestinal parasites

Bu araştırmanın amacı; mide-bağırsak parazitleriyle enfekte gebe akkaraman ırkı koyunlarda serum demir parametreleri, bakır ve demir eksikliği anemisini araştırmaktır. Araştırma 60 gebe akkaraman ırkı koyun üzerinde yürütüldü. İstatistiksel analizde, parazitli koyunlarda elde edilen değerler parazitle enfekte olmayan koyunların değerleriyle karşılaştırıldığında PCV (P < 0,05), Hb (P < 0,05), RBC (P < 0,05), total protein (P < 0,05), albümin (P < 0,05), globulin (P < 0,05), MCHC (P < 0,01) değerlerinde azalış ve WBC değerinde (P < 0.05) artış gözlendi. Ayrıca parazitli grubun parazitsiz gruba göre daha düşük serum Fe (P < 0,001), % TS (P < 0,001), serum Cu (P < 0,01) değerlere ve daha yüksek UIBC (P < 0,05) sahip olduğu saptandı. Sonuç olarak; parazitli gebe koyunlarda antiparaziter ilaç uygulamaların ek olarak aynı zamanda demir eksikliğini tedavi etmek için demir preparatları uygulanmalıdır.

Mide-bağırsak parazitleriyle enfekte gebe Akkaraman koyunlarda serum demir, total demir bağlama kapasitesi, demir bağlamama kapasitesi, transferrin doyum serum bakır ve bazı hematolojik parametreler

The aim of this study was to investigate serum iron parameters, and copper and iron deficiency anemia in ewes infected with gastro-intestinal parasites. This study was conducted with 60 pregnant Akkaraman ewes. In the statistical analyses, values obtained from both parasite infected and uninfected ewes were compared. Significant decreases were observed in PCV (P < 0.05), Hb (P < 0.05), RBC (P < 0.05), total protein (P < 0.05), albumin (P < 0.05), globulin (P < 0.05), and MCHC (P < 0.01), and a significant increase was seen in the WBC value (P < 0.05) in the parasite infected group. Furthermore, the parasite infected group had lower serum Fe (P < 0.001), TS % (P < 0.001), and serum Cu (P < 0.01) levels, and had higher UIBC values (P < 0.05) compared to the values obtain from the uninfected group. Therefore, in addition to antiparasite drug treatment in parasite infected pregnant ewes, iron preparations should also be administered in order to treat iron deficiency.

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1)Kaneko, J.J.: Iron metabolism and its disease. In: Clinical Biochemistry of Domestic Animals. 4th ed. Academic Press, New York, 1989:256-273.
2)Tapiero, H., Gate, L, Tew, K.D.: Iron: deficiencies and requirements. Biomed. Pharmacother., 2001; 55: 324-32.
3)Underwood, E.J., Suttle, N.F.: Iron. In: The Mineral Nutrition of Livestock, 3 rd ed. Biddies Ltd, London. 2001; 375-395.
4)Yılmaz, K., Özer, E., Erkal, N.: Studies on the caused by iron deficiency in parasite infested and free calves. Fırat Üni. Sağ. Bil. Derg., 1992; 7: 103-110.
5)Schalm, O.W., Jain, N.C., Carrol, E.J.: Veterinary Hematology. 3rd ed. Lea and Febiger, Philadelphia. 1975.
6)Burns, L.M., Titchener, R.N., Holmes, P.H.: Blood parameters and turnover data in calves infested with lice. Res. Vet. Sci., 1992; 52: 62-66.
7)Breymann, C: Iron deficiency and anaemia in pregnancy: modern aspects of diagnosis and therapy. Blood Cells Mol. Dis., 2002; 29: 506-516.
8)Barrionuevo, M., Alferez, M.J.M., Lopez Aliağa, I.. Sanz Sampelayo, M.R., Campos, M.S.: Beneficial effect of goat milk on nutritive utilization of iron and copper in malabsorption syndrome. J. Dairy Sci., 2002; 85: 657-664
9)Miyata, Y., Furugouri, K., Shijimaya, K.: Developmental changes in serum ferritin concentration of dairy calves. J. Dairy Sci., 1984; 67: 1256-1263.
10)Boch, J., Supperer, R.: Veterinaermedizinische Parasitogie, 3. Aufl. Paul Parey Verlag, Berlin, Hamburg, 1983.
11)Whitlock, H.V.: Some modification of the McMaster helminth egg- counting techniques and apparatus. J. Coun. Sci. Indust. Res., 1948:21:177-180.
12)Voyvoda, H., Sekin, S., Kaya, A., Bildik, A.: Modifications of serum, copper concentration (SI, Cu), total and latent iron- binding capacity (TIBC, LIBC), and transferrin saturation (TS) in natural Babesia ovis infection of ewes. Turk. J. Vet. Anim. Sci., 1997:21:31-37.
13)Miltenburg, G.A., Wensing, T., Van Vliet, J.P., Schuijt, G., van de Broek, J., Breukink, H.J.: Blood hemoglobin, plasma iron, and tissue iron in dams in late gestation, at calving, and in veal calves at delivery and later. J. Dairy Sci., 1991; 74: 3086-3094.
14)Jain, J.J.: Schalm's Veterinary Hematology, 4th Ed., Lea and Febiger, Philadelphia. 1986.
15)Kozat, S., Yüksek, N., Altuğ, N., Ağaoğlu, T.Z., Ercin, F.: Studies on the effect of iron (Fe) preparation in addition to babesiosis treatment on the hematological and some mineral levels in sheep naturally infected with Babesia ovis. Y.Y.Ü. Vet. Fak. Derg., 2003; 14: 18-21.
16)Jaber, L. S., Habre, A., Rawda, N., Abi Said, M., Barbour, E.K, Hamadeh, S.: The effect of water restriction on certain physiological parameters in Awassi sheep. Small Rum. Res., 2004:54:115-120.
17)Vatn, S., Framstad, T.: Anaemia in housed lambs: effects of oral iron on clinical pathology and performance. Acta Vet. Scand., 2000:41:273-281.
18)Trengove, C.L., Judson, G.J.: Trace element supplementation of sheep: evaluation of various copper supplements and a soluble glass bullet containing copper, cobalt and selenium. Aust. Vet. J., 1985:62:321-324.
19)Nazki, A.R., Rattan, P. J.S.: Status of blood micro-elements during different season in ewes. Indian Vet. J., 1990; 67: 274-276.