Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas

In a retrospective study on cytological specimens from 17 dogs with histologically confirmed cutaneous squamous cell carcinoma, the morphometric variables were studied and compared to tumors' nuclear grade. The morphometric parameters evaluated in this study were mean nuclear area (MNA, µm2), mean nuclear perimeter (MNP, µm), mean nuclear diameter (D mean, µm), minimum nuclear diameter (D min, µm), and maximum nuclear diameter (D max, µm). Associations between MNA, MNP, D mean, D min, and D max and tumors' grade were assessed using the ANOVA/LSD test (Statistica 6.0, StatSoft, USA) at a level of significance of P < 0.05. The result indicated an increase in the mean values of the nuclear parameters with increasing tumor grade. In the cases examined, significant differences in MNA, MNP, and D mean occurred between tumors in all grades. Besides, no significant differences in D max (between grade I-II and II-III) and D min (grade II-III) were found. In conclusion, nuclear morphometry could be used as an additional tool for differentiating nuclear grade in canine cutaneous squamous cell carcinomas.

Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas

In a retrospective study on cytological specimens from 17 dogs with histologically confirmed cutaneous squamous cell carcinoma, the morphometric variables were studied and compared to tumors' nuclear grade. The morphometric parameters evaluated in this study were mean nuclear area (MNA, µm2), mean nuclear perimeter (MNP, µm), mean nuclear diameter (D mean, µm), minimum nuclear diameter (D min, µm), and maximum nuclear diameter (D max, µm). Associations between MNA, MNP, D mean, D min, and D max and tumors' grade were assessed using the ANOVA/LSD test (Statistica 6.0, StatSoft, USA) at a level of significance of P < 0.05. The result indicated an increase in the mean values of the nuclear parameters with increasing tumor grade. In the cases examined, significant differences in MNA, MNP, and D mean occurred between tumors in all grades. Besides, no significant differences in D max (between grade I-II and II-III) and D min (grade II-III) were found. In conclusion, nuclear morphometry could be used as an additional tool for differentiating nuclear grade in canine cutaneous squamous cell carcinomas.

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Bibtex @ { tbtkveterinary150925, journal = {Turkish Journal of Veterinary and Animal Sciences}, issn = {1300-0128}, eissn = {1303-6181}, address = {}, publisher = {TÜBİTAK}, year = {2009}, volume = {33}, pages = {439 - 442}, doi = {}, title = {Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas}, key = {cite}, author = {Sımeonov, Radostin} }
APA Sımeonov, R . (2009). Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas . Turkish Journal of Veterinary and Animal Sciences , 33 (5) , 439-442 .
MLA Sımeonov, R . "Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas" . Turkish Journal of Veterinary and Animal Sciences 33 (2009 ): 439-442 <
Chicago Sımeonov, R . "Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas". Turkish Journal of Veterinary and Animal Sciences 33 (2009 ): 439-442
RIS TY - JOUR T1 - Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas AU - Radostin Sımeonov Y1 - 2009 PY - 2009 N1 - DO - T2 - Turkish Journal of Veterinary and Animal Sciences JF - Journal JO - JOR SP - 439 EP - 442 VL - 33 IS - 5 SN - 1300-0128-1303-6181 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Veterinary and Animal Sciences Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas %A Radostin Sımeonov %T Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas %D 2009 %J Turkish Journal of Veterinary and Animal Sciences %P 1300-0128-1303-6181 %V 33 %N 5 %R %U
ISNAD Sımeonov, Radostin . "Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas". Turkish Journal of Veterinary and Animal Sciences 33 / 5 (Mayıs 2009): 439-442 .
AMA Sımeonov R . Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas. Turkish Journal of Veterinary and Animal Sciences. 2009; 33(5): 439-442.
Vancouver Sımeonov R . Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas. Turkish Journal of Veterinary and Animal Sciences. 2009; 33(5): 439-442.
IEEE R. Sımeonov , "Nuclear morphometry in relation to tumor grade in canine spontaneous cutaneous squamous cell carcinomas", Turkish Journal of Veterinary and Animal Sciences, c. 33, sayı. 5, ss. 439-442, May. 2009
Turkish Journal of Veterinary and Animal Sciences
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

60.9b55.8b

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