Evaluation of two vaccination schemes using live vaccines against nexcastle disease in chickens
Evaluation of two vaccination schemes using live vaccines against nexcastle disease in chickens
The use of different types of Newcastle disease (ND) vaccine in different vaccination schemes has decreased the incidence of velogenic Newcastle disease (VND) in commercial poultry worldwide. In under-developed countries like Pakistan, these vaccination schemes are not successful due to free-range and backyard poultry production. This trial was conducted in 90 experimental chickens to develop an effective control against ND. The level of antibody response, detected by haemagglutination-inhibition (HI) test, and the degree of protection against the virulent strain of Newcastle disease virus (NDV) were studied. The chickens were immunized with commercially available ND vaccines. In scheme A, primary vaccination was done with La Sota vaccine with 109 E1D5O, administered on day 5 by eye drop (E/D), followed by a booster vaccination with the same vaccine and the same route on day 21 and, in scheme B, primary vaccination was done with the same vaccine (La Sota vaccine with 109 EID50), administered on day 5 by E/D, followed by a booster vaccination with a mesogenic strain (Mukteshwar) given intramuscularly on day 21. Both schemes of immunization conducted ensure comparatively solid immunity when challenged with a virulent field isolate of ND at 6 weeks of age. A better protection index was obtained from chickens vaccinated with scheme B.
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- 1.Mishra, S., Kataria, J.M., Verma, K.C., Sah, R.L.: Response of chickens to infection with Newcastle disease virus isolated from guinea fowl. Trop. Anim. Health Prod., 2000; 32: 277-284. 2.Gallili, G.E., Ben-Nathan, D.: Newcastle disease vaccines. Biotechnol. Adv., 1998; 16: 343-366. 3.Alexander, D.J.: Newcastle disease and other paramyxovirus infections, In: Calnek, B.W., Barnes, H.J., Beard, C.W., McDougal, L.R., Saif, Y.M. (Eds). Diseases of Poultry, 10th Ed., Iowa State Univ. Press, Ames, IA. 1997; 541-569. 4.Glision, G.R., Kleven S.H.: Poultry vaccines, In: Peters A.R., (Ed.). Vaccines for Veterinary Application, Butterworth-Heinemann, Ltd. Oxford, England. 1993; 165-173. 5.Chandraseker, S., Venkatesan, R.A., Padmanaban, V.D., Masiilamony, P.R.: Nature of protective immunity responses in chicken against Ranikhet disease, lnd. Vet. J., 1989; 66: 801- 806. 6.Jayawardane, G.W.L., Spradbrow, P.B.: Mucosal immunity in chickens vaccinated with the V4 strain of Newcastle disease virus. Vet. Microbiol., 1995; 46: 69-77. 7.Parry, S.H., Aitken, I.D.: İmmunoglobulin A in the respiratory tract of the chicken following exposure to Newcastle disease virus. Vet. Rec, 1973; 93: 258-260. 8.Folitse, R., Halvorson, D.A., Sivanandan, V.: Efficacy of combined killed-in-oil emulsion and live Newcastle disease vaccines in chickens. Avian Dis., 1998; 42: 173-178. 9.Van Eck, J.H.H.: Immunity to Newcastle Disease in fowl of different breeds primarily vaccinated with commercial inactivated oil-emulsion vaccines: a laboratory experiment. Vet. Q., 1987; 9: 296-303. 10.Tizard, I.R.: Veterinary Immunology: An Introduction; 7th Ed., W.B: Saunders Company, Philadelphia. 2004; 263-264. 11.Reed, L.J., Muench, H.: A simple method for fifty percent end point. Am. J. Hyg., 1938; 27: 493-496. 12.Allan, W.H., Gough, R.E.: A standard haemagglutination inhibition test for Newcastle disease. I. A comparison of macro and micro methods. Vet. Rec, 1974; 95: 120-123. 13.Steel, R.G.D., Torrie, J.H.: Principles and Procedures of Statistics, 2nd Ed., McGraw-Hill Book Co. Inc., New York. 1982; 137-171. 14.Majid-Zadeh, A., Kita, J., Mayan, M.H., Saheb-Chalan, D.: Observation on flock immunity to Newcastle disease after routine vaccination and experimental aerosol vaccination. Pol. Arch. Wete., (Warszawa), 1980; 21: 477-483. 15.Voeten, A.C., Orthel, F.W., Jacobs, J.: Comparison of live Newcastle disease vaccines in a simple vaccination and challenge experiment. Res. Vet. Sci., 1977; 22: 138-145. 16.Westbury, H.A.: Comparison of the immunogenicity of Newcastle disease virus strain V4, Hitchner B1 and La Spta in chickens. 1. Tests in susceptible chickens. Aust. Vet. J., 1984; 61: 5-9. 17.Giambrone, J.J.: Laboratory evaluation of Newcastle disease vaccination programs for broiler chickens. Avian Dis., 1985; 29: 479-487. 18.Tizard, I.R.: Veterinary Immunology. 5th Ed. W.B. Saunders Company, Philadelphia. 1996; 251-263. 19.Mrzel, I., Josipovic, D., Cajavec, S., Cizelj, A., Viduka, D., Tuta, I., Vasari, K.: Immunization of broilers in the hatchery against infectious bronchitis and Newcastle disease with bivalent live vaccines. Praxis Vet. Zagreb, 1992; 40: 279-292; (with abstract in English) 20.Winterfield, R.W., Dhillon, A.S., Alby, L.J., Vaccination of chickens against Newcastle disease with live and inactivated Newcastle disease virus. Poult. Sci., 1980; 59: 240-246. 21.Khadzhiev, G., Obreshkov, K., Kiretchiev, G.: Vaccination schemes against Newcastle disease in poultry. Vet. Med. Nauki, 1979; 16: 56-65. (with abstract in English)