Effects of various Toxeat® concentrations on growth performance, immune response, cecal microflora, and gut morphology in broilers fed with aflatoxin contaminated diets

Effects of various Toxeat® concentrations on growth performance, immune response, cecal microflora, and gut morphology in broilers fed with aflatoxin contaminated diets

This study was conducted to investigate the effects of Toxeat®, a mycotoxin binder, on functional indices, immune response,intestinal microflora, and gut morphology in broiler chickens fed aflatoxin-contaminated diets. Three hundred Cobb 500 broilers wererandomly divided into 6 treatments with 5 replicates, each with 10 birds. The treatments included T1: negative control (NC), T2: T1 +1 g/ton aflatoxin (positive control: PC), T3: PC + 1 kg/ton Toxeat®, T4: PC + 2 kg/ton Toxeat®, T5: PC + 3 kg/ton Toxeat®, T6: PC + 1 kg/ton Toxeat® without hydrated sodium calcium aluminosilicate. Growth performance, immune system response, and lactic acid bacteria(LAB) count decreased in the PC group (P < 0.05). Surprisingly, humoral and cellular immune response significantly increased in theToxeat® treatments (P < 0.05). Besides, administration of Toxeat® significantly increased weight gain and LAB count compared with thePC group at the end of experiment (P < 0.05), whereas intestinal morphology showed no significant changes (P > 0.05). Finally, Toxeat®administration (1–2 kg/ton) resulted in the best growth performance and immunity.

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