Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats

Öz This study aimed to investigate the treatment outcomes of topical application of boric acid, boron-doped gel, and ozonated olive oil in cases of Microsporum canis -induced dermatophytosis. Furthermore, the outcomes were compared to those of terbinafine administration. We included 39 female Wistar albino rats weighing 200-250 g and created an M. canis-infected area on the skin of their backs. The rats were clinically scored on days 0, 7, 14, 21, and 28 and underwent histopathological evaluation. All the treated groups demonstrated significantly lower clinical scores than the control group P < 0.05 . Fewer inflammation cells were observed in the samples of groups treated with 3% boric acid and sodium pentaborate pentahydrate gel than in those of the control group. According to the histopathological evaluation, the groups treated with 3% boric acid and sodium pentaborate pentahydrate gel were statistically different from the control and other treatment groups P < 0.05 . Our results indicated that treatment with 3% boric acid and sodium pentaborate gel was adequate in resolving M. canis -induced infection in rats. Therefore, gels containing 3% boric acid and sodium pentaborate pentahydrate may be alternatives to antifungal agents such as terbinafine by ensuring easy, reliable, inexpensive, and effective treatment modalities.

Kaynakça

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Kaynak Göster

Bibtex @ { tbtkveterinary724436, journal = {Turkish Journal of Veterinary and Animal Sciences}, issn = {1300-0128}, eissn = {1303-6181}, address = {}, publisher = {TÜBİTAK}, year = {2020}, volume = {44}, pages = {258 - 265}, doi = {10.3906/vet-1910-51}, title = {Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats}, key = {cite}, author = {Gezer, Ayhan Hilal and Acar, Abuzer} }
APA Gezer, A , Acar, A . (2020). Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats . Turkish Journal of Veterinary and Animal Sciences , 44 (2) , 258-265 . DOI: 10.3906/vet-1910-51
MLA Gezer, A , Acar, A . "Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats" . Turkish Journal of Veterinary and Animal Sciences 44 (2020 ): 258-265 <https://dergipark.org.tr/tr/pub/tbtkveterinary/issue/53838/724436>
Chicago Gezer, A , Acar, A . "Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats". Turkish Journal of Veterinary and Animal Sciences 44 (2020 ): 258-265
RIS TY - JOUR T1 - Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats AU - Ayhan Hilal Gezer , Abuzer Acar Y1 - 2020 PY - 2020 N1 - doi: 10.3906/vet-1910-51 DO - 10.3906/vet-1910-51 T2 - Turkish Journal of Veterinary and Animal Sciences JF - Journal JO - JOR SP - 258 EP - 265 VL - 44 IS - 2 SN - 1300-0128-1303-6181 M3 - doi: 10.3906/vet-1910-51 UR - https://doi.org/10.3906/vet-1910-51 Y2 - 2021 ER -
EndNote %0 Turkish Journal of Veterinary and Animal Sciences Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats %A Ayhan Hilal Gezer , Abuzer Acar %T Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats %D 2020 %J Turkish Journal of Veterinary and Animal Sciences %P 1300-0128-1303-6181 %V 44 %N 2 %R doi: 10.3906/vet-1910-51 %U 10.3906/vet-1910-51
ISNAD Gezer, Ayhan Hilal , Acar, Abuzer . "Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats". Turkish Journal of Veterinary and Animal Sciences 44 / 2 (Mart 2020): 258-265 . https://doi.org/10.3906/vet-1910-51
AMA Gezer A , Acar A . Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats. Turkish Journal of Veterinary and Animal Sciences. 2020; 44(2): 258-265.
Vancouver Gezer A , Acar A . Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats. Turkish Journal of Veterinary and Animal Sciences. 2020; 44(2): 258-265.
IEEE A. Gezer ve A. Acar , "Effects of boron compounds and ozonated olive oil on experimental Microsporum canis ınfection in rats", Turkish Journal of Veterinary and Animal Sciences, c. 44, sayı. 2, ss. 258-265, Mar. 2020, doi:10.3906/vet-1910-51

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