A micromorphometric study on the common bile duct and major duodenal papilla of the domestic swine

Abstract: The aim of the current study was to perform a comparative micromorphometric study on the thickness of mucosa, fibromuscular layer, glandular zone, serosa, and subserous layer, as well as of the entire wall of extra- and intramural parts of the porcine common bile duct in immature and mature animals. This micromorphometric study also evaluated the height and width of the lining epithelium, glandular epithelium, and goblet cells in 2-month, 6-month, and 3-year old male pigs. It was found that significant age-dependent differences in the studied parameters exist. Some differences in the studied parameters were also detected between different parts of the common bile duct, as well as between the common bile duct and major duodenal papilla in pigs of the same age. Immunohistochemical staining with smooth muscle actin, and Van Gieson and Orcein staining were performed to distinguish the smooth muscle cells and collagenous and elastic fibers. In conclusion, age dependent differences in the studied parameters in the porcine common bile duct and major duodenal papilla were detected.Key words: Common bile duct, major duodenal papilla, morphometry, glands, goblet cells, swine

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