ANDAÇ SALMAN, Merve Hatun SARIÇAM, AYŞE DENİZ YÜCELTEN, Cuyan DEMİRKESEN, SAFİYE ATLAS TÜLİN ERGUN

Neonatal lupus erythematosus: Report of a case with cutaneous, hematological and hepatobiliary findings

ISSN: 0041-4301
Yayın Aralığı: Yılda 6 Sayı
Başlangıç: 1958
Yayıncı: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü Müdürlüğü

Neonatal lupus erythematosus is an autoimmune disorder mainly affecting the heart and skin. It is the most common cause of congenital heart block. In addition, hematological, hepatobiliary and neurological involvement may occur. Herein, we report a 23-day-old infant presented with annular, erythematous, and scaly and atrophic lesions on the face and trunk. Based on the clinical, laboratory and histopathological findings, she was diagnosed as neonatal lupus erythematosus. Neonatal lupus eryhtematosus should be considered in infants presenting with annular skin lesions, and we present this case to highlight the value of high index of clinical suspicion in diagnosis

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1. Lee LA. Neonatal Lupus erythematosus: clinical findings and pathogenesis. J Investig Dermatol Symp Proc 2004; 9: 52-56.

2. Boh EE. Neonatal Lupus erythematosus. Clin Dermatol 2004; 22: 125-128.

3. Wisuthsarewong W, Soongswang J, Chantorn R. Neonatal lupus erythematosus: clinical character, investigation and outcome. Pediatr Dermatol 2011; 28: 115-121.

4. Moretti D, Cimaz R, Vannucci G, Marino A, De Martino M, Greco A. Cutaneous neonatal lupus: a case report and review of the literature. Int J Dermatol 2014; 53: 1508-1512.

5. Inzinger M, Salmhofer W, Binder B. Neonatal Lupus erythematosus and its clinical variability. J Dtsch Dermatol Ges 2012; 10: 407-410.

6. Lee LA. The clinical spectrum of neonatal lupus. Arch Dermatol Res 2009; 301: 107-110.

7. Toledo-Alberola F, Betloch-Mas I. Annular erythema of infancy. Actas Dermosifiliogr 2010; 101: 473-484.