Investigation of the relationship between cord clamping time and risk of hyperbilirubinemia

Background. Although the relationship between umbilical cord clamping time and various parameters such as hemoglobin (Hb) levels, iron deficiency, and risk of neonatal jaundice has previously been studied, to the best of our knowleadge there have been no studies investigating the relationship between cord clamping time and the risk of significant hyperbilirubinemia. We aimed to investigate the relationship between the time of umbilical cord clamping and transcutaneous bilirubin (TcB) measurements made on various postnatal hours, Hb and serum total bilirubin (STB) levels measured on postnatal 4th day, and the risk of development of significant hyperbilirubinemia requiring phototherapy treatment. Methods. Eligible newborns were divided into two groups on the basis of the time of cord clamping: those clamped late (60 seconds or more; Group I) and those clamped early (less than 60 seconds; Group II). Groups were compared with respect to the parameters of cord Hb, postnatal TcB measurements at 6th, 48th, 96th and 168th hours, and 96th hour Hb, STB and direct bilirubin levels. Results. TcB levels at the 96th and 168th hour were significantly higher in Group I when compared to Group II (p

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1.Wyllie J, Bruinenberg J, Roehr CC, Rüdiger M, Trevisanuto D, Urlesberger B. European Resuscitation Council Guidelines for Resuscitation 2015: section 7. resuscitation and support of transition of babies at birth. Resuscitation 2015; 95: 249-263.

2.McDonald S. Physiology and management of the third stage of labour. In: Fraser DM, Cooper MA, (eds). Myles Textbook for Midwives. (14th ed) Edinburgh: Churchill Livingstone, 2003.

3.Mercer JS. Current best evidence: a review of the literature on umbilical cord clamping. J Midwifery Womens Health 2001; 46: 402-414.

4.Palethorpe RJ, Farrar D, Duley L. Alternative positions for the baby at birth before clamping the umbilical cord. Cochrane Database Syst Rev 2010; 10: CD007555.

5.Nakagawa M, Ishida Y, Nagaoki Y, et al. Correlation between umbilical cord hemoglobin and rate of jaundice requiring phototherapy in healthy newborns. Pediatr Int 2015; 57: 626-628.

6.American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004; 114: 297-316.

7.Maisels MJ, Bhutani VK, Bogen D, Newman TB, Stark AR, Watchko JF. Hyperbilirubinemia in the newborn infant ≥35 weeks’ gestation: an update with clarifications. Pediatrics 2009; 124: 1193-1198.

8.Ceriani Cernadas JM, Carroli G, Pellegrini L, et al. The effect of timing of cord clamping on neonatal venous hematocrit values and clinical outcome at term: a randomized, controlled trial. Pediatrics 2006; 117: e779-e786.

9.Mercer JS, Erickson-Owens DA, Collins J, Barelos MO, Parker AB, Padbury JF. Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial. J Perinatol 2017; 37: 260-264.

10.Nesheli HM, Esmailzadeh S, Haghshenas M, Bijani A, Moghaddams TG. Effect of late vs early clamping of the umbilical cord (on hemoglobin level) in full-term neonates. J Pak Med Assoc 2014; 64: 1303-1305.

11.McDonald SJ, Middleton P, Dowswell T, Morris PS. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Evid Based Child Health 2014; 9: 303-397.

12.Rabe H, Diaz-Rossello J, Duley L, Dowswell T. Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. Cochrane Database Syst Rev 2012; 8: CD003248.

13.Chien PC, Yang CC, Gau ML, Liu CY, Lee TY. The impact of late umbilical cord clamping on neonatal jaundice and postpartum hemorrhage: a randomized controlled trial. Hu Li Za Zhi 2015: 62; 41-53.

14.Yang S, Duffy JY, Johnston R, Fall C, Fitzmaurice LE. Association of a delayed cord-clamping protocol with hyperbilirubinemia in term neonates. Obstet Gynecol 2019; 133: 754-761.

15.Committee on Obstetric Practice. Delayed umbilical cord clamping after birth. Committee Opinion. The American College of Obstetricians and Gynecologists. Obstetr Gynecol 2017; 129: e5-e10.
Turkish Journal of Pediatrics-Cover
  • ISSN: 0041-4301
  • Yayın Aralığı: 6
  • Başlangıç: 1958
  • Yayıncı: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü Müdürlüğü
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