The Epidemiology of Microsporidias in Humans (Malatya sample)

Aim: Microsporidias, first isolated and defined in 1857, are obligate intracellular parasites observed in animal groups and especially invertebrates. Generally homosexual patients and patients who are HIV positive and immune suppressed constitute the participants of international studies about the epidemiology of microsporidias. No previous studies about the prevalence of the parasite in Turkey have been found in the literature. This study aimed to determine the epidemiology of microsporidias in and around Malatya. Materials and Methods: Feces samples (n: 2665) from patients who presented at İnönü University Medical Faculty policlinics in 2006 with some digestive system complaints and were referred to the Parasitology Department were analyzed. The samples were analyzed using modified trichrome (MTS), Acid-Fast-Trichrome, Calcofluor, and Giemsa staining. Results: In all 226 samples (8.5%) were positive. There was a statistically significant relationship between lack of appetite, general body pruritus, immune suppression + cancer, dyspnea, and ulcerative colitis. Conclusions: It is important to check feces samples for Microsporidium spp. parasites regularly for cases including unexplained diarrhea, stomachache, lack of appetite, general pruritus, immune suppression + cancer, asthma, and ulcerative colitis, since Microsporidium spp. is not a commonly known parasite in Turkey.

The Epidemiology of Microsporidias in Humans (Malatya sample)

Aim: Microsporidias, first isolated and defined in 1857, are obligate intracellular parasites observed in animal groups and especially invertebrates. Generally homosexual patients and patients who are HIV positive and immune suppressed constitute the participants of international studies about the epidemiology of microsporidias. No previous studies about the prevalence of the parasite in Turkey have been found in the literature. This study aimed to determine the epidemiology of microsporidias in and around Malatya. Materials and Methods: Feces samples (n: 2665) from patients who presented at İnönü University Medical Faculty policlinics in 2006 with some digestive system complaints and were referred to the Parasitology Department were analyzed. The samples were analyzed using modified trichrome (MTS), Acid-Fast-Trichrome, Calcofluor, and Giemsa staining. Results: In all 226 samples (8.5%) were positive. There was a statistically significant relationship between lack of appetite, general body pruritus, immune suppression + cancer, dyspnea, and ulcerative colitis. Conclusions: It is important to check feces samples for Microsporidium spp. parasites regularly for cases including unexplained diarrhea, stomachache, lack of appetite, general pruritus, immune suppression + cancer, asthma, and ulcerative colitis, since Microsporidium spp. is not a commonly known parasite in Turkey.

___

  • Buget E, Buyukbaba-Boral O, Kırkoyun-Uysal H, Nazlıcan O, Ogut T, Sengur G. First Case Report in Turkey: Microsporidiosis and Pulmonary Cryptosporidiosis in an AIDS Patient. Turkish Microbiological Society 2000; 30: 166-170.
  • Ozkirim A, Keskin N. A survey of Nosema apis of honey bees (Apis mellifera L.) producing the famous Anzer honey in Turkey. Z Naturforsch [C] 2001; 56: 918-9.
  • Eröksüz H, Eröksüz Y, Metin N, Özer H. Morphological analysis on natural encephalitozoonosis keys among a rabbit colony. Tr J Veterinary Animal Sciences 1999; 23: 191-95.
  • Yaman M, Radek R. Nosema chaetocnemae sp.n. (Microspora: Nosematidae), a microsporidian parasite of Chaetocnema tibialis (Coleoptera: Chrysomelidae), Acta Protozool 2003; 42: 231- 237.
  • Müller A, Stellerman K, Hartmann PIA. A powarful DNA extraction method and PCR for detection of Microsporidia in clinical stool specimens. Clin Diagn Lab Immunol 1999; 6: 243-246.
  • Field AS, Hing MC, Milliken ST, Marriott DJ. Microsporidia in the small intestine of HIV-infected patients. A new diagnostic technique and a new species. Med J Aust 1993; 15: 390-4.
  • Fournier S, Liguory O, Sarfati C, David-Ouaknine F, Derouin F, Decazes JM. Disseminated infection due to Encephalitozoon cuniculi in a patient with AIDS: case report and review. HIV Med 2000; 1: 155-161.
  • Brasil P, de Lima DB, de Paiva DD, Lobo MS, Sodré FC, Silva SP et al. Microsporidiosis in HIV-infected patients with chronic diarrhea in Rio De Janeiro, Brazil. Rev Inst Med Trop S Paulo 2000; 42: 299-304.
  • Bretagne S, Foulet F, Alkassoum W, Fleury-Feith J, Develoux M. Prevalence of Enterocytozoon bieneusi spores in the stool of AIDS patients and African children not infected by HIV, Bull Soc Pathol Exot 1993; 86: 351-7.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

The Significance of DNA Ploidy in the Malignant Potential of Colorectal Adenocarcinomas

Yavuz ÖZORAN, Etem ALHAN, Hayrettin ÇIRAY, Yavuz TEKELİOĞLU, Ümit ÇOBANOĞLU

The Effect of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole on the Cell Death Induced by Zinc Administration in the Brain of Rats

Aysel GÜVEN, Faruk BAĞIRICI, M. Ömer BOSTANCI, M. Fatih GÖKÇE, Şerif DEMİR

Could Obstructive Sleep Apnea Syndrome be a Component of Metabolic Syndrome?

Asiye KANBAY, Ulukavak Tansu ÇİFTÇİ, Oğuz KÖKTÜRK

Prevalence of Hepatitis B Infection among Schoolchildren in Southeast Turkey

Ayfer GÖZÜ, Hakan UZUN, Bünyamin DİKİCİ, Mücahit FİDAN

The problem of antimicrobial resistance in nosocomial medical and surgical ıntensive care units ınfections in a university hospital; a two-year prospective study

Akgün YAMAN, Refik BURGUT, Şaban İNCECİK, İbrahim KARAYAYLALI, Mehmet ÖZALEVLİ, Neşe SALTOĞLU, Murat GÜNDÜZ

Local Reccurence of Giant Renal Cell Carcinoma without Distant Metastases 25 Years after Radical Nephrectomy

Özkan POLAT, İsa ÖZBEY, Yılmaz AKSOY, Turgut YAPANOĞLU, Cemal GÜNDOĞDU

Association between Mean Platelet Volume and Autonomic Nervous System Functions: Increased Mean Platelet Volume Reflects Sympathetic Overactivity

Hüseyin AYHAN, Özcan ÖZDEMİR, Telat KELEŞ, Tahir DURMAZ, Murat AKÇAY, Ekrem YETER, Akar Nihal BAYRAM, Engin BOZKURT

A Simple Surgical Technique for Repair of Iridodialysis

Mehmet Cüneyt ÖZMEN, Şengül ÖZDEK

Vocal Cord Hemangioma; A Rare Localization in Adults

Şefik Halit AKMANSU, Muharrem DAĞLI, Ayşe İRİZ, Levent ALBAYRAK, Adil ERYILMAZ, Evrim DURMAZ

The Epidemiology of Microsporidias in Humans (Malatya sample)

Ülkü KARAMAN, Metin ATAMBAY, Nilgün DALDAL, Cemil ÇOLAK