The diagnostic value of ischemia-modified albumin in the diagnosis of aortic pathology

To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.

The diagnostic value of ischemia-modified albumin in the diagnosis of aortic pathology

To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

The diagnostic value of ischemia-modified albumin in the diagnosis of aortic pathology

Oğuz EROĞLU, Süha TÜRKMEN, Ahmet MENTEŞE, Gökalp ALTUN, Süleyman TÜREDİ, Umut ERYİĞİT, Süleyman Caner KARAHAN, Abdülkadir GÜNDÜZ

Choroidal thickness in healthy Turkish subjects

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Is perioperative examination of frozen sections necessary in nephron-sparing surgery?

Mehmet KALKAN, Soner YALÇINKAYA, Coşkun ŞAHİN, Yeşim ÜÇKURT, Ömer ETLİK