Demet ETİT, Süheyla CUMURCU, Fatma Nur AKTAŞ, Deniz ALTINEL, Rafet BEYHAN, Naciye Ümit BAYOL

Documentation of small intestine atresias: a single-institution experience in Turkey (22 cases)

To investigate the associated anomalies and causes of death in a neonatal autopsy series with intestinal atresias over an 8-year period from the archives of our department. Intestinal atresia, meaning the complete absence of a segment of the intestine or complete occlusion of the intestinal lumen, is the most common cause of gastrointestinal obstruction in neonatal autopsy series. There is an approximately equal sex distribution. Materials and methods: From the archives of our records, 22 cases with intestinal atresia were reevaluated. The patients' demographic data were noted. Anomalies associated with intestinal atresia were grouped into systemic categories and the main causes of death were documented. Results: There was a female predominancy with an average life span of 10 days. Neonates with prematurity or low birth weight made up the vast majority of the series (95.5%). Duodenal atresia was seen in 11 cases (50%). The anomaly most frequently associated with intestinal atresia was detected in the gastrointestinal system, as well (77.2%). The most common cause of death was bacterial sepsis, at 50%. Conclusion: Intestinal atresias are one of the significant anomalies among perinatal autopsy cases and need to be carefully investigated by pathologists.

Anahtar Kelimeler:

Key words: Intestinal atresia, autopsy

Documentation of small intestine atresias: a single-institution experience in Turkey (22 cases)

Keywords:

Key words: Intestinal atresia, autopsy,

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Dahms Barrett B. Th e respiratory tract. In: Stocker JT, editor. Pediatric pathology. 1st ed. Philadelphia: Lippincott Co.; 1992. p.662-664.
Desa D. Th e alimentary tract. In: Wigglesworth JS, editor. Textbook of fetal and perinatal pathology. 1st ed. Boston: Blackwell Scientifi c Publications; 1991. p.927-933.
Choudhry MS, Rahman N, Boyd P, Lakhoo K. Duodenal atresia: associated anomalies, prenatal diagnosis and outcome. Pediatr Surg Int 2009; 25: 727-730. 4. Dalla Vecchia LK, Grosfeld JL, West KW, Rescorla FJ, Scherer LR, Engum SA. Intestinal atresia and stenosis: a 25-year experience with 277 cases. Arch Surg 1998; 133: 490-496; discussion 496-497.
Wilinson AW. Congenital causes of duodenal obstruction. J R Coll Surg Edinb 1973; 18: 197-208.
Spitz L, Ali M, Brereton RJ. Combined esophageal and duodenal atresia: experience of 18 patients. J Pediatr Surg 1981; 16: 4-7.
Reid IS. Biliary tract anomalies associated with duodenal atresia. Arch Dis Child 1973; 48: 952-957.
Longo MF, Lynn HB. Congenital duodenal obstruction: review of 29 cases encountered in a 30-year period. Mayo Clin Proc 1967; 42: 423-430.
Jona JZ, Belin RP. Duodenal anomalies and the ampulla of Vater. Surg Gynecol Obstet 1976; 143: 565-569.
Girvan DP, Stephens CA. Congenital intrinsic duodenal obstruction: a twenty-year review of its surgical management and consequences. J Pediatr Surg 1974; 9: 833-839.
Fonkalsrud EW, DeLorimier AA, Hays DM. Congenital atresia and stenosis of the duodenum. A review compiled from the members of the Surgical Section of the American Academy of Pediatrics. Pediatrics 1969; 43: 79-83.
Burjonrappa SC, Crete E, Bouchard S. Prognostic factors in jejuno-ileal atresia. Pediatr Surg Int 2009; 25: 795-798.