Demographics, clinical presentations and outcomes of cancer patients admitted to the emergency department

Amaç: Kanser hastalarının tedavisinde yeni stratejilerin geliştirilmesi bu hastaların acil servislere artan sayıda başvurularına neden olmaktadır. Bu çalışma acil servise başvuran kanser hastalarının karakteristiklerinin belirlenmesini ve kısa dönem sağkalımı belirleyen faktörlerin araştırılmasını amaçlamaktadır. Yöntem ve Gereç: Bu ileriye dönük gözlemsel klinik çalışma yıllık hasta sayısı 55.000 olan bir üniversite hastanesi acil servisinde yapılmıştır. Altı aylık sürede acil servise başvuran tüm kanser hastaları çalışmaya dahil edilmiş ve acil servis başvurusu sonrasında birinci ve üçüncü aylarında takip edilmişlerdir. Kayıtlar hastanın geliş şikayetlerini, detaylı demografik bilgilerini ve sağlık durumlarını içeren bir anket formu doldurularak elde edilmiştir. Bulgular: Çalışma süresi içerisinde acil servise başvuran 245 kanser hastasının 324 başvurusu değerlendirildi. Acil servise en sık başvuru sebebi bulantı, kusma ve ağrıydı. Hastaneye yatırılma oranı 324 başvuru için % 37.3 idi. Toplam 245 hastanın 44’ü (% 18) ilk 1 ay içerisinde 77’si (% 31.4) 3 ayın sonunda hayatını kaybetti. Aktif kanser mevcudiyeti, performans skorunun 4 olması ve acil serviste periferik dama yolu dışında bir girişim uygulanmış olması 3 aylık sağkalımın anlamlı belirleyicileri olarak bulundu. Sonuç: Kanser hastalarında etkin ağrı yönetimi ve anti emetic kullanımı hastane dışında tedavisi planlanan hastalarda acil servis başvurularını azaltabilir. Acil Servis doktorları kanser hastalarının acil servis değerlendirmelerinde kısa dönem sağkalımları ile ilgili risk faktörlerini dikkate alabilirler.

Acil servise başvuran kanser hastalarının klinik, demografik ve prognostik özellikleri

Aim: The development of new treatment strategies for cancer patients resulted in an increase of cancer patient visits to emergency departments (EDs). The purpose of this study is to determine clinical characteristics, causes, and predictors of short term prognosis of cancer patient admissions to the ED. Materials and Methods: This prospective, clinical, and observational study was carried out in an adult ED of a tertiary hospital with an annual census of 55,000. All cancer patients visiting the ED within the 6-month period were enrolled into the study and followed up at the 1st and 3rd months afterwards. Records were based on a questionnaire including the patient’s main complaint, detailed demographics, and health status. Results: During the study period, 324 visits of 245 cancer patients were recorded and evaluated. The most common complaints of ED visits were nausea, vomiting, and pain. Hospitalization rate for the 324 visits was 37.3%. Of the 245 patients, 44 (18%) died within a month, and a further 77 (31,4%) within 3 months. Presence of an active disease, performance score of 4, and procedure other than peripheral venous access were the factors predicting the 3-month mortality. Conclusions: Effective pain and antiemetic management at outpatient oncology departments can decrease cancer patients’ ED visits. ED physicians might consider certain risk factors indicating higher mortality in short term in order to plan patients’ ED management.

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  • 1. Turkey Health Report. February 2004 Ankara. Publication number: SB-HM-2004/01,(http://www.sabem.saglik.gov.tr/ forum/ezadmin/htmlarea/files/documents/1252_7türkiye_saglik_ raporu_2003.pdf)
  • 2. Kilicaslan I, Bozan H, Oktay C, Goksu E. Demographic Properties of patients presenting to the ED in Turkey. Turkish Journal of Emergency Medicine 2005; 5: 5-13.
  • 3. Bozcuk H, Koyuncu E, Yildiz M, Samur M, Ozdogan M, Artac M et al. A simple and accurate prediction model to estimate the intrahospital mortality risk of hospitalised cancer patients. Int J Clin Pract 2004; 58(11): 1014-9.
  • 4. Tas F, Aykan F, Alici S, Kaytan E, Aydiner A, Topuz E. Prognostic factors in pancreatic carcinoma: serum LDH levels predict survival in metastatic disease. Am J Clin Oncol 2001; 24(6): 547-50.
  • 5. Sculier JP, Paesmans M, Markiewicz E, Berghmans T. Scoring systems in cancer patients admitted for an acute complication in a medical intensive care unit. Crit Care Med 2000; 28(8): 2786-92.
  • 6. Porta M, Malats N, Morell E, Gomez G, Gallen M, Macia F et al. Decreased survival of patients with lung cancer admitted to a teaching hospital through the emergency department in Barcelona, Spain. J Epidemiol Community Health. 1998; 52(2): 137-8.
  • 7. Cornill C, Verger E, Salamero M. Performance status assessment in cancer patients.Cancer 1990; 65(8): 1864-6.
  • 8. Porta M, Fernandez E, Belloc J, Malats N, Gallen M, Alonso J. Emergency admission for cancer: a matter of survival? Br J Cancer. 1998; 77(3): 477-84.
  • 9. Polednak AP. Inpatient hospital admission through an emergency department in relation to stage at diagnosis of colorectal cancer. Cancer Detect Prev. 2000; 24(3): 283-9.
  • 10. McArdle CS, Hole DJ. Emergency presentation of colorectal cancer is associated with poor 5-year Survival. Br J Surg. 2004 May; 91(5): 605-9.
  • 11. Blackshaw GR, Stephens MR, Lewis WG, Paris HJ, Barry JD, Edwards P et al. Prognostic significance of acute presentation with emergency complications of gastric cancer. Gastric Cancer. 2004; 7(2): 91-6.
  • 12. Geraci JM, Tsang W, Valdres RV, Escalante CP. Progressive disease in patients with cancer presenting to an emergency room with acute symptoms predicts short-term mortality. Support Care Cancer. 2006 Mar 30; [Epub ahead of print].
  • 13. Swenson KK, Rose MA, Ritz L, Murray CL, Adlis SA. Recognition and evaluation of oncology-related symptoms in the emergency department. Ann Emerg Med 1995; 26: 12-17.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
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