4919

Antifungal Activities of Different Extracts and Echimidine-N-oxide from Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. Sepulcrale

Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.

Anahtar Kelimeler:

Symphytum sylvaticum, pyrrolizidine alkaloids, echimidine-N-oxide, antifungal activity, GC analysis

Antifungal Activities of Different Extracts and Echimidine-N-oxide from Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. Sepulcrale

Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.

Keywords:

Symphytum sylvaticum, pyrrolizidine alkaloids, echimidine-N-oxide, antifungal activity, GC analysis,

Turkish Journal of Medical Sciences-Cover

ISSN: 1300-0144
Yayın Aralığı: Yılda 6 Sayı
Yayıncı: TÜBİTAK

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