This study was conducted in an endemic goitre area to determine thyroid profiles TSH, freeT4 (fT4), T4, fT3 and T3, as well as the degree of the severity of hypothyroidism and the prevalence of the disease. Tonbak is a small village in Kahramanmaraş. The iodine content of the water is < 1 mg/L. A randomly selected group of 121 subjects aged 16-55 were included in the study. The percentage of goitre was 71.1% upon physical examination. Subjects with primary hypothyroidism were 16.5%. Mean scores of fT4 were 8.9±2.6 pmol/l (range: 2.7-12.9) and mean scores of TSH were 18.1±26.1 mU/ml (range: 4.33-100

This study was conducted in an endemic goitre area to determine thyroid profiles TSH, freeT4 (fT4), T4, fT3 and T3, as well as the degree of the severity of hypothyroidism and the prevalence of the disease. Tonbak is a small village in Kahramanmaraş. The iodine content of the water is < 1 mg/L. A randomly selected group of 121 subjects aged 16-55 were included in the study. The percentage of goitre was 71.1% upon physical examination. Subjects with primary hypothyroidism were 16.5%. Mean scores of fT4 were 8.9±2.6 pmol/l (range: 2.7-12.9) and mean scores of TSH were 18.1±26.1 mU/ml (range: 4.33-100