Beril DİLBER, Ayşe AKSOY, Mukaddes KALYONCU, Enbiya DİLBER, Erol ERDUMAN, Murat ÇAKIR

Acute pancreatitis as an atypical presentation of Henoch-Schonlein purpura and cystic fibrosis

Acute pancreatitis (AP) is a rare clinical entity in childhood. Two children, aged 10 and 14 years, were hospitalized for acute abdominal pain. Clinical and laboratory findings were compatible with AP. Both patients were given supportive medications. Two days after admission, the first patient had purpuric lesions on both buttocks and lower extremities, and occult bleeding. The clinical picture was consistent with Henoch-Schonlein purpura, with pancreatitis and gastrointestinal involvement. The patient’s clinical condition improved rapidly after administration of prednisolone. The second patient had digital clubbing on physical examination, and positive sweat chloride test results led to the diagnosis of cystic fibrosis. AP in association with Henoch-Schonlein purpura and the initial manifestations of cystic fibrosis is very rare, and the presentation of these conditions is discussed.

Anahtar Kelimeler:

Key words: acute pancreatitis, cystic fibrosis, Henoch-Schonlein purpura

Acute pancreatitis as an atypical presentation of Henoch-Schonlein purpura and cystic fibrosis

Keywords:

Key words: acute pancreatitis, cystic fibrosis, Henoch-Schonlein purpura,

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Werlin SL, Kugathasan S, Frautschy BC. Pancreatitis in children. J Pediatr Gastroenterol Nutr. 2003; 37: 591-5.
Garner JA. Acute pancreatitis as a complication of anaphylactoid (Henoch-Schönlein) purpura. Arch Dis Child 1977; 52: 971-2. 8. Cheung KM, Mok F, Lam P, Chan KH. Pancreatitis associated with Henoch-Schonlein purpura. J Paediatr Child Health 2001; 37: 311-3. 9. Soyer T, Egritas O, Atmaca E, Akman H, Oztürk H, Tezic T. Acute pancreatitis: a rare presenting feature of Henoch Schonlein purpura. J Paediatr Child Health 2008; 44: 152-3.
Branski D, Gross V, Gross-Kieselstein E, Roll D, Abrahamov A. Pancreatitis as a complication of Henoch-Schonlein purpura. J Pediatr Gastroenterol Nutr 1982; 1: 275-6.
Chen SY, Kong MS. Gastrointestinal manifestations and complications of Henoch-Schönlein purpura. Chang Gung Med J 2004; 27: 175-81.
De Boeck K, Weren M, Proesmans M, Kerem E. Pancreatitis among patients with cystic fibrosis: correlation with pancreatic status and genotype. Pediatrics 2005; 115: 463-9.
Augarten A, Ben Tov A, Madgar I, Barak A, Akons H, Laufer J, et al. The changing face of the exocrine pancreas in cystic fibrosis: the correlation between pancreatic status, pancreatitis and cystic fibrosis genotype. Eur J Gastroenterol Hepatol 2008; 20: 164-8.