A bacteriological examination of urine before and after urodynamic testing
Urodynamic studies have been associated with an increased risk of bacteriuria and symptomatic urinary tract infection (UTI) because it is applied by invasive catheterization. In this study the value of antibiotic prophylaxis in decreasing the risk of bacteriuria and symptomatic UTI has been questioned in children. Materials and methods: Urine samples of 90 patients, who were taken before and after urodynamic testing in Cerrahpaşa Faculty of Medicine Videourodynamics Laboratory of Child Surgery Department, were cultured microbiologically to determine the presence of bacteriuria. Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin prophylaxis after the urodynamics (P < 0.05) compared to pre-urodynamics. According to our results, the most frequently bacteria detected before urodynamic testing was E. coli (in 25 patients, 3 of them ESBL + strains) as it was the same as post-urodynamics. Conclusion: As a result, we suggest that it will be necessary to evaluate prophylactic usage of trimethoprim-sulfamethoxazole and nitrofurantoin. The isolation of some nosocomial infectious agents is considered as another significant point of our study. ESBL + E. coli and Enterococcus faecium strains, which were isolated from patients under prophylaxis, showed the importance of this kind of surveillance studies.
A bacteriological examination of urine before and after urodynamic testing
Urodynamic studies have been associated with an increased risk of bacteriuria and symptomatic urinary tract infection (UTI) because it is applied by invasive catheterization. In this study the value of antibiotic prophylaxis in decreasing the risk of bacteriuria and symptomatic UTI has been questioned in children. Materials and methods: Urine samples of 90 patients, who were taken before and after urodynamic testing in Cerrahpaşa Faculty of Medicine Videourodynamics Laboratory of Child Surgery Department, were cultured microbiologically to determine the presence of bacteriuria. Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin prophylaxis after the urodynamics (P < 0.05) compared to pre-urodynamics. According to our results, the most frequently bacteria detected before urodynamic testing was E. coli (in 25 patients, 3 of them ESBL + strains) as it was the same as post-urodynamics. Conclusion: As a result, we suggest that it will be necessary to evaluate prophylactic usage of trimethoprim-sulfamethoxazole and nitrofurantoin. The isolation of some nosocomial infectious agents is considered as another significant point of our study. ESBL + E. coli and Enterococcus faecium strains, which were isolated from patients under prophylaxis, showed the importance of this kind of surveillance studies.
___
- Emir H. Anorektal malformasyonlara eşlik edebilen nörovezikal disfonksiyonların ürodinamik tanısı. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, İstanbul. Uzmanlık tezi 1993. 2.
- Gomes CM, Arab S, Trigo-Rocha F. Voiding dysfunction and
- urodynamic abnormalities in elderly patients. Rev Hos Clin Fac
- Matsumato T, Sakumato M, Takahashi K, Kumazawa J. Prevention of catheter associated urinary tract infection by meatal disinfection . Dermatology, 1997; 195: 73-77.
- Ulutan F, Taş N. Hastane infeksiyonu olarak idrar yolu infeksiyonları. İnfeksiyon Derg 1989; 3: 451.
- Leblebicioğlu H. Nozokomiyal üriner sistem infeksiyonu: Etkenler ve direnç. Hastane İnfek Derg 1999 3: 70-73.
- Shekarriz B, Upadhyay J, Freedman AL, Fleming P, Barthold JS, Gonzalez R. Lack of morbidity from urodynamic studies in children with asymptomatic bacteriuria. Urology 1999; 54: 359- 361.
- Olson ES, Cookson BD. Do antimicrobials have a role in preventing septicaemia following instrumentation of the urinary tract. J Hospital Infect 2000; 45: 85-97.
- Cundiff GW, Mclennan MT, Bent AE. Randomized trial of antibiotic prophylaxis for combined urodynamics and cystourethroscopy. Obstetrics Gynecology, 1999; 93: 749-752.
- Grabe M. Controversies in antibiotic prophyloxis in urology. J Antimicrob Agents 2004; 23S1: S17-S23.
- Okorocha I, Cuming G, Gould I. Female urodynamics and lower urinary tract infection. BJU International 2002; 89: 863- 867.
- Quek P, Tay LH. Morbidity and significant bacteriuria after urodynamic studies. Ann Acad Med Singapore 2004; 33: 754- 757.