Meryem ÇAKIR, Deniz ALMAK, Kurtuluş ÖNGEL

AİLE HEKİMLİĞİNDE NADİR GÖRÜLEN BİR OLGU: ACETAMİPRİD ZEHİRLENMESİ

Neonikotinoidler, yeni bir insektisid grubu olup, özellikle mahsullerin korunmasında yaygın olarak kullanılmaktadır. Aile Hekimliği uygulamalarında, acetamiprid gibi insektisitlere bağlı zehirlenmeler ile nadirende olsa karşılaşılabilmektedir. Semptomları, pek çok hastalık ile karışabilen acetamiprid zehirlenmesinin birinci basamak hekimlerince tanınabilmesi önemlidir. Bu vaka takdimi ile, %20 acetamipride deri ve inhalasyon yolu ile maruziyet sonrası, klinik semptom gelişen 40 yaşında bir erkek hastaya klinik yaklaşımın sunulması amaçlanmıştır.

Anahtar Kelimeler:

Aile hekimliği, acetamiprid, toksisite

A Rare Case in Family Medicine: Acetamiprid Poisoning

Neonicotinoids are a new insecticide group; It is widely used especially for crop protection. In family medicine practices, poisoning due to insecticides such as acetamiprid may rarely be encountered. It is important to recognize acetamiprid poisoning, whose symptoms can be confused with many diseases, by primary care physicians. With this case report, it is aimed to present the clinical approach to a 40-year-old male patient who developed clinical symptoms after exposure to 20% acetamiprid via skin and inhalation.

Keywords:

Family medicine, acetamiprid, toxicity,

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1. Tomizawa M, Casida JE. Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol 2005;45:247–68.
2. Nauen R, Denholm I. Resistance of insectpests to neonicotinoid insecticides: current status and future prospects. Arch Insect Biochem Physiol 2005;58:200–15.
3. Elbert A, Haas M, Springer B, Thielert W, Nauen R. Applied aspects of neonicotinoid uses in cropprotection. Pest Manag Sci 2008;64:1099–105.
4. Lin PC, Lin HJ, Liao YY, Guo HR, Chen KT. Acute Poisoning with Neonicotinoid Insecticides: A Case Report and Literature Review. Basic & Clinical Pharmacology & Toxicology 2013;112:282–6.
5. Kimura-Kuroda, J, Komuta Y, Kuroda Y, Hayashi M, Kawano H. Nicotine-Like Effects of the Neonicotinoid Insecticides Acetamiprid and Imidacloprid on Cerebellar Neurons from Neonatal Rats. PLoS ONE 2012;7(2):e32432.
6. Harada KH, Tanaka K, Sakamoto H, Imanaka M, Niisoe T, Hitomi, T et al. Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics. PLOS ONE 2016;11(1):e0146335.
7. Allen J. The European Definition of General Practice / Family Medicine, Wonca Europe, Barcelona, 2005.
8. Imamura T, Yanagawa Y, Nishikawa K, Matsumoto N, Sakamoto T. Two cases of acute poisoning with acetamiprid in humans. Clin Toxicol (Phila). 2010 Oct;48(8):851-3.
9. Yang Y, Ma S, Liu F, Wang Q, Wang X, Hou C. Acute and chronic toxicity of acetamiprid, carbaryl, cypermethrin and deltamethrin to Apis mellifera larvae reared in vitro. Pest Manag Sci. 2020 Mar;76(3):978-85.
10. Fidancı İ, Öztürk O. Asitresin kullanımına bağlı hipertrigliseridemi olgusu. Smyrna Tıp Dergisi 2018;8(3):44-6.
11. Ateş E, Set T. Biyopsikososyal Yaklaşım. Turkiye Klinikleri J Fam Med-Special Topics. 2017;8(2):93-5.