Anıl Oğuz EROĞLU, Orhan Murat KOÇAK, Şadiye Visal BUTURAK, Figen COŞKUN, Ayşe Gül ÖZPOLAT YILMAZ, Turğut DENİZ

Karbonmonoksit zehirlenmesinin mizaç üzerindeki etkisi

Amaç: Bu çalışma karbonmonoksit zehirlenmesinin mizaç ve ilişkili olduğu bozukluklar üzerindeki etkisini araştırmak amacıyla yapılmıştır.Gereç ve Yöntemler: Çalışma Kırıkkale Üniversitesi hastanesi acil servisine karbonmonoksit (CO) maruziyeti sebebiyle başvuran hastalar ve sağlıklı gönüllü (SG) katılımcılarla yapıldı. Karboksihemoglobin düzeyi ≥%10 ölçülen hastalar KZ olarak kabul edildi. Psikiyatrik hastalığı veya ilaç kullanımı olanlar ve CO düzeyini yükseltecek hastalığı veya sigara içiciliği olanlar çalışmaya dahil edilmedi. SG bir kere, KZ olanlar ise acil servise ilk başvuru anında taburcu edilirken ve taburcu olduktan üç ay sonra TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionaire) mizaç ölçeği ile değerlendirildi. Grupların karşılaştırılmasında Repeated measures ANOVA testi kullanıldı ve p<0.05 anlamlı kabul edildi. Bulgular: Çalışmaya KZ (n=68) ve SG (n=42) olmak üzere toplam 110 katılımcı dahil edildi. Gruplar TEMPS-A mizaç ölçeği puanları bakımından karşılaştırıldığında, acil servise ilk başvuru anında Depresif (p=0.016) ve Anksiyöz (p=0.01) mizaç, üçüncü ayda ise Irritable (p=0.02) ve Anksiyöz (p=0.034) mizaç tipi puanlarında anlamlı farklılık saptandı. KZ olan hastaların mizaç ölçeği puanları, değerlendirme zamanına (İlk başvuru zamanı ve üçüncü ay) göre karşılaştırıldığında hiçbir mizaç tipinde fark saptanmadı. Sonuç: KZ sonrası hastaların özellikle depresyon ve anksiyete ile ilişkisi olan mizaç tiplerinde etkilenme olsa da, mizaç özellikleri tamamen değişmemiştir. Karbonmonoksit zehirlenmesinin psikiyatrik etkilerinin daha iyi anlaşılabilmesi için ileri çalışmalara ihtiyaç vardır.

Anahtar Kelimeler:

acil servis, mizaç, Karbomonoksit zehirlenmesi, psikiyatrik bozukluklar, mizaç ölçeği

Effects of carbon monoxide poisoning on temperament

Aim: The aim of this study was to investigate the effect of carbon monoxide (CO) poisoning on temperament and associated disorders.Material and Methods: The study was conducted in healthy volunteers and patients who presented to the Emergency Department of Kirikkale University Hospital after exposure to CO. Patients with a carboxyhemoglobin level of ≥10% were considered to have CO poisoning. Patients with psychiatric disease or an illness that could increase CO levels and those who smoked or were using medication were excluded. Healthy volunteers were evaluated once, and CO poisoning patients were evaluated at the time of presentation and 3 months after discharge using the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A) temperament scale. Repeated analysis of variance was applied for comparisons. A p value of <0.05 was considered statistically significant.Results: The study included 110 participants: 68 in the CO poisoning group and 42 healthy volunteers. Significant differences between the groups were observed in the TEMPS-A scores for depressive type (p=0.016) and anxious type (p=0.01) at first presentation and for the irritability type (p=0.02) and anxious type (p=0.034) at 3 months after the discharge. When the temperament scale scores of the CO poisoning patients were compared according to evaluation time (first presentation and 3 months after discharge), no significant difference in temperament types was observed. Conclusion: Although the temperament types related to depression and anxiety were affected after CO poisoning, they did not change completely. Further research is needed to better understand the psychiatric effects of CO poisoning.

Keywords:

Carbonmonoxide poisoning, emergency department, temperament, psychiatric disorders, temperament scale,

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