Transition Metal Compound Mediated Reduction of a-Amino Acids to 1,2-Amino Alcohols with NaBH4 in Water

A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.

Transition Metal Compound Mediated Reduction of a-Amino Acids to 1,2-Amino Alcohols with NaBH4 in Water

A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.
Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

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Transition Metal Compound Mediated Reduction of a-Amino Acids to 1,2-Amino Alcohols with NaBH4 in Water

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