Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides
Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.
Anahtar Kelimeler:
N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) substituted benzamides, antifungal
Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides
Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.
- ISSN: 1300-0527
- Yayın Aralığı: Yılda 6 Sayı
- Yayıncı: TÜBİTAK
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