A highly sensitive method was investigated for the simultaneous determination of dopamine (DA), uric acid (UA), and tryptophan (TRP) using a multiwall carbon nanotubes/5-amino-3',4'-dimethoxy-biphenyl-2-ol modified carbon paste electrode (5ADMBCNPE). The 5ADMBCNPE displayed excellent electrochemical catalytic activities towards the oxidation of DA, UA, and TRP. The electrochemical profile of the proposed modified electrode was analyzed by cyclic voltammetry (CV), which showed a shift in the oxidation peak potential of DA at 160 mV to a less positive value compared with an unmodified carbon paste electrode. Square wave voltammetry (SWV) in 0.1 M phosphate buffer solution (PBS) at pH 7.0 was performed to determine DA in the range from 1.2 to 800.0 m M, with a detection limit of 0.16 m M. The present method was applied to the determination of DA in some real samples.

A highly sensitive method was investigated for the simultaneous determination of dopamine (DA), uric acid (UA), and tryptophan (TRP) using a multiwall carbon nanotubes/5-amino-3',4'-dimethoxy-biphenyl-2-ol modified carbon paste electrode (5ADMBCNPE). The 5ADMBCNPE displayed excellent electrochemical catalytic activities towards the oxidation of DA, UA, and TRP. The electrochemical profile of the proposed modified electrode was analyzed by cyclic voltammetry (CV), which showed a shift in the oxidation peak potential of DA at 160 mV to a less positive value compared with an unmodified carbon paste electrode. Square wave voltammetry (SWV) in 0.1 M phosphate buffer solution (PBS) at pH 7.0 was performed to determine DA in the range from 1.2 to 800.0 m M, with a detection limit of 0.16 m M. The present method was applied to the determination of DA in some real samples.