Effect of Surfactants on Response of Promethazine PVC-Membranes

The effect of surfactants (cationic, anionic and non-ionic) on the performance of plastic membrane promethazine electrodes was studied. Three electrodes with membranes containing either sodium tetraphenylborate, sodium tetraphenylborate + 18-crown-6, or 18-crown-6 were prepared. The cationic and the anionic surfactants exhibited potential shifts and a super-Nernstian slope of the calibration graphs. The non-ionic surfactant did not cause alterations in the calibration graphs. The effect of surfactants' concentrations was investigated. The performance characteristics of these electrodes were studied. The slopes of the calibration graphs of the 3 electrodes were 54.4, 54.9 and 48.4 mV/decade. The rectilinear ranges were 2 x 10-5-10-2, 1.0 x 10-5-10-2 and 3.2 x 10-5-10-2 M corresponding to the 3 electrodes. The optimum pH range was 2-7. The selectivity coefficient values were calculated for different inorganic cations, amino acids and pharmaceutical amines. Direct potentiometry and potentiometric titration were applied for the determination of promethazine in its pure form or in its pharmaceutical preparation. The recovery range and the relative standard deviation values for potentiometric titration were 98.6%-100.1% and 0.79%-1.96% (4 determinations), respectively. For direct potentiometry, the corresponding recovery values were 98.6% and 99.5%, and the relative standard deviation values were 1.49% and 1.02% (4 determinations).

Effect of Surfactants on Response of Promethazine PVC-Membranes

The effect of surfactants (cationic, anionic and non-ionic) on the performance of plastic membrane promethazine electrodes was studied. Three electrodes with membranes containing either sodium tetraphenylborate, sodium tetraphenylborate + 18-crown-6, or 18-crown-6 were prepared. The cationic and the anionic surfactants exhibited potential shifts and a super-Nernstian slope of the calibration graphs. The non-ionic surfactant did not cause alterations in the calibration graphs. The effect of surfactants' concentrations was investigated. The performance characteristics of these electrodes were studied. The slopes of the calibration graphs of the 3 electrodes were 54.4, 54.9 and 48.4 mV/decade. The rectilinear ranges were 2 x 10-5-10-2, 1.0 x 10-5-10-2 and 3.2 x 10-5-10-2 M corresponding to the 3 electrodes. The optimum pH range was 2-7. The selectivity coefficient values were calculated for different inorganic cations, amino acids and pharmaceutical amines. Direct potentiometry and potentiometric titration were applied for the determination of promethazine in its pure form or in its pharmaceutical preparation. The recovery range and the relative standard deviation values for potentiometric titration were 98.6%-100.1% and 0.79%-1.96% (4 determinations), respectively. For direct potentiometry, the corresponding recovery values were 98.6% and 99.5%, and the relative standard deviation values were 1.49% and 1.02% (4 determinations).

Kaynak Göster

Bibtex @ { tbtkchem142550, journal = {Turkish Journal of Chemistry}, issn = {1300-0527}, eissn = {1303-6130}, address = {}, publisher = {TÜBİTAK}, year = {2006}, volume = {30}, pages = {307 - 323}, doi = {}, title = {Effect of Surfactants on Response of Promethazine PVC-Membranes}, key = {cite}, author = {Zareh, Mohsen M. and Abd-el-fatah, Raga E. Shohiab And Mostafa} }
APA Zareh, M , Abd-el-fatah, R . (2006). Effect of Surfactants on Response of Promethazine PVC-Membranes . Turkish Journal of Chemistry , 30 (3) , 307-323 .
MLA Zareh, M , Abd-el-fatah, R . "Effect of Surfactants on Response of Promethazine PVC-Membranes" . Turkish Journal of Chemistry 30 (2006 ): 307-323 <
Chicago Zareh, M , Abd-el-fatah, R . "Effect of Surfactants on Response of Promethazine PVC-Membranes". Turkish Journal of Chemistry 30 (2006 ): 307-323
RIS TY - JOUR T1 - Effect of Surfactants on Response of Promethazine PVC-Membranes AU - Mohsen M. Zareh , Raga E. Shohiab And Mostafa Abd-el-fatah Y1 - 2006 PY - 2006 N1 - DO - T2 - Turkish Journal of Chemistry JF - Journal JO - JOR SP - 307 EP - 323 VL - 30 IS - 3 SN - 1300-0527-1303-6130 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Chemistry Effect of Surfactants on Response of Promethazine PVC-Membranes %A Mohsen M. Zareh , Raga E. Shohiab And Mostafa Abd-el-fatah %T Effect of Surfactants on Response of Promethazine PVC-Membranes %D 2006 %J Turkish Journal of Chemistry %P 1300-0527-1303-6130 %V 30 %N 3 %R %U
ISNAD Zareh, Mohsen M. , Abd-el-fatah, Raga E. Shohiab And Mostafa . "Effect of Surfactants on Response of Promethazine PVC-Membranes". Turkish Journal of Chemistry 30 / 3 (Mart 2006): 307-323 .
AMA Zareh M , Abd-el-fatah R . Effect of Surfactants on Response of Promethazine PVC-Membranes. Turk J Chem. 2006; 30(3): 307-323.
Vancouver Zareh M , Abd-el-fatah R . Effect of Surfactants on Response of Promethazine PVC-Membranes. Turkish Journal of Chemistry. 2006; 30(3): 307-323.
IEEE M. Zareh ve R. Abd-el-fatah , "Effect of Surfactants on Response of Promethazine PVC-Membranes", Turkish Journal of Chemistry, c. 30, sayı. 3, ss. 307-323, Mar. 2006
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

10.9b 6.5b