Nurettin YAYLI, Asu USTA, Ahmet YAŞAR, Osman ÜÇÜNCÜ

Cyclic Triterpenoid Saponins from Campanula lactiflora

Two cyclic natural compounds, 3b-O-[a-L-rhamnopyranosyl- (1 \to 2)-b-D-glucopyranosyl]-13a,14a-epoxy-8a,12b, 15-trihydroxy-(17E,21E)-17,21-campanuldien-6'(30)-olide, called lactifloroside A, 1, and 3b-O-[b-D-glucopyranosyl-(1 \to 2)-b-D-glucopyranosyl]- 13a,14a-epoxy-8a,12b-dihydroxy-(17E,21E)-17,21-campanuldien- 6'(30)-olide, called lactifloroside B, 2, were isolated for the first time from Campanula lactiflora and their structures deduced by high field 1D and 2D 400 MHz NMR, FT-IR, HPLC, GC-MS, (+/-) LC-MS/MS and (+) FAB-MS spectra. The aglycones of the 2 saponins were named 13a,14a-epoxy-3b,8a,12b,15-tetrahydroxy-(17E,21E)- 17,21-campanuldien-30-oic acid and 13a,14a-epoxy-3b,8a, 12b-trihydroxy-(17E,21E)-17,21-campanuldien-30-oic acid, and designated as campanuloic acid and 15-deoxycampanuloic acid, respectively.

Anahtar Kelimeler:

Campanula lactiflora, lactifloroside A and B, campanuloic acid, 15-deoxycampanuloic acid, cyclic bisdemoside

Cyclic Triterpenoid Saponins from Campanula lactiflora

Keywords:

Campanula lactiflora, lactifloroside A and B, campanuloic acid, 15-deoxycampanuloic acid, cyclic bisdemoside,

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