Chemistry of Bicyclic Endoperoxides Derived from Dihydropyridine Derivatives: Attempted Synthesis of Polyhydroxypiperidine Derivatives

To achieve the synthesis of azasugar derivatives with the utilization of singlet oxygen, pyridine was used as the starting material. The reduction of pyridine followed by a singlet oxygen reaction afforded cyclic aza-endoperoxides (14 and 16). However, many attempts were made to convert the aza-endoperoxides to the corresponding di- and triacetates without success. However, the base-catalyzed rearrangement of 14 gave unprecedented rearrangement products 23 and 24.

Anahtar Kelimeler:

Azasugar derivatives, amino sugars, singlet oxygen, bicyclic endoperoxides

Chemistry of Bicyclic Endoperoxides Derived from Dihydropyridine Derivatives: Attempted Synthesis of Polyhydroxypiperidine Derivatives

Keywords:

Azasugar derivatives, amino sugars, singlet oxygen, bicyclic endoperoxides,

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