Some thermodynamic quantities were obtained for the interactions of poly [2-(3-mesityl-3-methylcyclobutyl)-2-hydroxyethyl methacrylate] with alcohols, ketones, acetates, aromatics and alkanes by inverse gas chromatography in the temperature range 160-200°C. The specific retention volumes, $Vg^o$, weight fraction activity coefficients of solute probes at infinite dilution, $Omega_1^infty$, Flory-Huggins thermodynamic interaction parameters, $X_{12}^infty$ between polymer and solvents were determined. The partial molar free energy, $Delta bar{G}_1^infty$, the partial molar heat of mixing, $Deltabar{H}_1^infty$ at infinite dilution and the solubility parameters of the polymer, $delta_2$ were calculated.