Zaheer AHMAD, Sajid MEHMOOD, Rehana IFZAL, Abdul MALIK

8491

A New Ursane-type Triterpenoid from Salvia santolinifolia

Santolinoic acid (1), a new ursane-type triterpene was isolated from the chloroform soluble fraction of Salvia santolinifolia. Its structure was established as 2a, 3b, 9a-trihydroxyurs-12-en-28-oic acid on the basis of spectroscopic analysis, including high resolution mass spectroscopy, and 1- and 2-dimensional NMR techniques. The compound (1) showed inhibitory activity against the enzymes acetylcholinesterase and butyrylcholinesterase.

Anahtar Kelimeler:

Salvia santolinifolia, Labiatae, triterpenoid, enzyme inhibition

A New Ursane-type Triterpenoid from Salvia santolinifolia

Santolinoic acid (1), a new ursane-type triterpene was isolated from the chloroform soluble fraction of Salvia santolinifolia. Its structure was established as 2a, 3b, 9a-trihydroxyurs-12-en-28-oic acid on the basis of spectroscopic analysis, including high resolution mass spectroscopy, and 1- and 2-dimensional NMR techniques. The compound (1) showed inhibitory activity against the enzymes acetylcholinesterase and butyrylcholinesterase.

Keywords:

Salvia santolinifolia, Labiatae, triterpenoid, enzyme inhibition,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: 6
Yayıncı: TÜBİTAK

Arşiv

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