___

• Aguilera CM, Mesa MD, Ramírez-Tortosa MC, Quiles JL, Gil A (2003). Virgin olive and fish oils enhance the hepatic antioxidant defence system in atherosclerotic rabbits. Clin Nutr 22: 379–384.
• Aguilera CM, Ramírez-Tortosa CL, Quiles JL, Yago MD, Martínez- Burgos MA, Martínez-Victoria E, Gil A, Ramírez-Tortosa MC (2005). Monounsaturated and omega-3 but not omega-6 polyunsaturated fatty acids improve hepatic fibrosis in hypercholesterolemic rabbits. Nutrition 21: 363–371.
• Allinguant B, Clamagirand C, Potier MC (2014). Role of cholesterol metabolism in the pathogenesis of Alzheimer´s disease. Curr Opin Clin Nutr Metab Care 17: 319–323.
• Ballesta MC, Mañas M, Matáix FJ, Martínez-Victoria E, Seiquer I (1990). Long-term adaptation of pancreatic response to dietary fats of different degrees of saturation: olive oil and sunflower oil. Br J Nutr 64: 487–496.
• Bogan JS , Xu Y, Hao M (2012). Cholesterol accumulation increases insulin granule size and impairs membrane trafficking. Traffic 13: 1466–1480.
• Borel P, Armand M, Senft M, Andre M, Lafont H, Lairon D (1991). Gastric lipase: evidence of an adaptive response to dietary fat in the rabbit. Gastroenterology 100: 1582–1589.
• Chowdhury P, Nishikawa M, Blevins GW Jr, Rayford PL (2000). Response of rat exocrine pancreas to high-fat and high- carbohydrate diets. Proc Soc Exp Biol Med 223: 310–315.
• Cortes VA, Busso D, Maiz A, Arteaga A, Nervi F, Rigotti A (2014). Physiological and pathological implications of cholesterol. Front Biosci 19: 416–428.
• Díaz RJ, Yago MD, Martínez-Victoria E, Naranjo JA, Martínez MA, Mañas M (2003). Comparison of the effects of dietary sunflower oil and virgin olive oil on rat exocrine pancreatic secretion in vivo. Lipids 38: 1119–1126.
• Emde C, Liehr RM, Gregor M, Pleul O, Riecken EO, Menge H (1985). Lack of adaptive changes in human pancreatic amylase and lipase secretion in response to high-carbohydrate, low-fat diet applied by a 10-day continuous intraduodenal infusion. Dig Dis Sci 30: 204–210.
• Erlanson-Albertsson C, Larsson A, Duan R (1987). Secretion of pancreatic lipase and colipase from rat pancreas. Pancreas 2: 531–535.
• Fernández ML, Webb D (2008). The LDL to HDL cholesterol ratio as a valuable tool to evaluate coronary heart disease risk. J Am Coll Nutr 27: 1–5.
• Flores CA, Brannon PM, Bustamante SA, Bezerra J, Butler KT, Goda T, Koldovský O (1988). Effect of diet on intestinal and pancreatic enzyme activities in the pig. J Pediatr Gastroenterol Nutr 7: 914–921.
• Gondré-Lewis M, Petrache HI, Wassif CA, Harries D, Parsegian A, Porter FD, Loh YP (2006). Abnormal sterols in cholesterol- deficiency diseases cause secretory granule malformation and decreased membrane curvature. J Cell Sci 119: 1876–1885.
• González-Santiago M, Martín-Bautista E, Carrero JJ, Fonollá J, Baró L, Bartolomé MV, Gil-Loyzaga E, López-Huertas E (2006). One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis 188: 35–42.
• Hao M, Head WS, Gunawardana SC, Hasty AH, Piston DW (2007). Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic β-cell dysfunction. Diabetes 56: 2328–2338.
• Hickson JCD (1970). The secretion of pancreatic juice in response to stimulation of the vagus nerves in the pig. J Physiol 206: 275–297.
• Jacobs LR (1983). Effect of short-term dietary fat on cell growth in rat gastrointestinal mucosa and pancreas. Am J Clin Nutr 37: 361–367.
• Kraft ML (2013). Plasma membrane organization and function: moving past liquid rafts. Mol Biol Cell 24: 2765–2768.
• Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ, Erdman JW Jr, Kris-Etherton P, Goldberg IJ, Kotchen TA et al. (2001). Revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. J Nutr 131: 132–146.
• Lepage G, Roy CC (1986). Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27: 114–120.
• Lin Y, Tamakoshi A, Hayakawa T, Naruse S, Kitagawa M, Ohno Y (2005). Nutritional factors and risk of pancreatic cancer: a population-based case-control study based on direct interview in Japan. J Gastroenterol 40: 297–301.
• Lippincott-Schwartz J, Phair RD (2010). Lipids and cholesterol as regulators of traffic in the endomembrane system. Annu Rev Biophys 39: 559–578.
• López-Palomo V, Martínez-Victoria E, Yago MD, Lupiani MJ, Mañas M (1997). Regulation by diet of the pancreas enzyme content of suckling goats. Arch Physiol Biochem 105: 566–571.
• Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265–275.
• Marshall LL, Stimpson SE, Hyland R, Coorssen JR, Myers SJ (2014). Increased lipid droplet accumulation associated with a peripheral sensory neuropathy. J Chem Biol 7: 67–76.
• Martínez MA, Lajas AI, Yago MD, Redondo PC, Granados MP, González A, Rosado A, Martínez-Victoria E, Mañas M, Pariente JA (2004). Dietary virgin olive oil enhances secretagogue-evoked calcium signaling in rat pancreatic acinar cells. Nutrition 20: 536–541.
• Maxfield FR, Tabas I (2005). Role of cholesterol and lipid organization in disease. Nature 438: 612–621.
• Meldolesi J, Jamieson JD, Palade GE (1971). Composition of cellular membranes in the pancreas of the guinea pig. I. Isolation of membrane fractions. J Cell Biol 49: 109–129.
• Muriana FJ, Vázquez CM, Ruiz-Gutiérrez V (1992). Fatty acid composition and properties of the liver microsomal membrane of rats fed diets enriched with cholesterol. J Biochem 112: 562–567.
• Noelting G, Bernfield P (1948). Sur les enzymes amylolytiques III. La β-amylase: dosage d’activité et contrôle de l’absence de α-amylase. Helv Chim Acta 31: 286–290.
• Nothlings U, Wilkens LR, Murphy SP, Hankin JH, Henderson BE, Kolonel LN (2005). Meat and fat intake as risk factors for pancreatic cancer: the multiethnic cohort study. J Natl Cancer Inst 97: 1458–1465.
• Ntambi JM (1999). Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 40: 1549–1558.
• Okada S, York DA, Bray GA (1993). Procolipase mRNA: tissue localization and effects of diet and adrenalectomy. Biochem J 292: 787–789.
• Paeratakul S, Ferdinand DP, Champagne CM, Ryan DH, Bray GA (2003). Fast-food consumption among US adults and children: dietary and nutrient intake profile. J Am Diet Assoc 103: 1332– 1338.
• Prinz W (2002). Cholesterol trafficking in the secretory and endocytic systems. Semin Cell Dev Biol 13: 197–203. Quiles JL, Mesa MD, Ramírez-Tortosa CL, Aguilera CM, Battino M, Gil A, Ramírez-Tortosa MC (2002). Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. Arterioscler Thromb Vasc Biol 22: 1225–1231.
• Rakonczay Z Jr, Jarmay K, Kaszaki J, Mandi Y, Duda E, Hegyi P, Boros I, Lonovics J, Takacs T (2003). NF-kappaB activation is detrimental in arginine-induced acute pancreatitis. Free Radic Biol Med 34: 696–709.
• Reboud JP, Ben Abdeljlil A, Desnuelle P (1962). Variations in the enzyme content of the rat pancreas as a function of the composition of the diet. Biochim Biophys Acta 58: 326–337.
• Roebuck BD, Yager JD Jr, Longnecker DS, Wilpone SA (1981). Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res 41: 3961–3966.
• Rydzewska G, Jurkowska G, Dzieciol J, Faszczewska A, Wroblewski E, Gabryelewicz A (2001). Does chronic ethanol administration have influence on pancreatic regeneration in the course of caerulein induced acute pancreatitis in rats. J Physiol Pharmacol 52: 835–849.
• Sabb JE, Godfrey PM, Brannon PM (1986). Adaptive response of rat pancreatic lipase to dietary fat: effects of amount and type of fat. J Nutr 116: 892–899.
• Saraux B, Girard-Globa A, Ouagued M, Vacher D (1982). Response of the exocrine pancreas to quantitative and qualitative variations in dietary lipids. Am J Physiol 243: G10–G15.
• Serrano P, Yago MD, Mañas M, Calpena R, Matáix J, Martínez- Victoria E (1997). Influence of type of dietary fat (olive and sunflower oil) upon gastric acid secretion and release of gastrin, somatostatin, and peptide YY in man. Dig Dis Sci 42: 626–633.
• Smith JG, Luk K, Schulz CA, Engert JC, Do R, Hindy G, Rukh G, Dufresne L, Almgren P, Owens DS et al. (2014). Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis. JAMA 312: 1764–1771.
• Soccio RE, Breslow JL (2004). Intracellular cholesterol transport. Arterioscler Thromb Vasc Biol 24: 1150–1160.
• Song Y, Joung H, Engelhardt K, Yoo SY, Paik HY (2005). Traditional v. modified dietary patterns and their influence on adolescents’ nutritional profile. Br J Nutr 93: 943–949.
• Snook JT (1971). Dietary regulation of pancreatic enzymes in the rat with emphasis on carbohydrate. Am J Physiol 221: 1383–1387.
• Sullan RM, Li JK, Hao C, Walker GC, Zou S (2010). Cholesterol- dependent nanomechanical stability of phase-segregated multicomponent lipid bilayers. Biophys 99: 507–516.
• Uyy E, Ivan L, Boteanu RM, Suica VI, Antohe F (2013). High-fat diet alters protein composition of detergent-resistant membrane microdomains. Cell Tissue Res 354: 771–778.
• Wang Y, Thiele C, Huttner WB (2000). Cholesterol is required for the formation of regulated and constitutive secretory vesicles from the trans-Golgi network. Traffic 1: 952–962.
• Wicker C, Puigserver A (1990) Expression of rat pancreatic lipase gene is modulated by a lipid-rich diet at a transcriptional level. Biochem Biophys Res Commun 166: 358–364.
• World Health Organization (2003). Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation. Geneva: World Health Organization.
• Yago MD, Díaz RJ, Martínez MA, Audi N, Naranjo JA, Martínez- Victoria E, Mañas M (2006). Effects of the type of dietary fat on acetylcholine-evoked amylase secretion and calcium mobilization in isolated rat pancreatic acinar cells. J Nutr Biochem 17: 242–249.
• Yago MD, Díaz RJ, Ramírez R, Martínez MA, Mañas M, Martínez- Victoria E (2004). Dietary-induced changes in the fatty acid profile of rat pancreatic membranes are associated with modifications in acinar cell function and signalling. Br J Nutr 91: 227–234.
• Yago MD, González MV, Martínez-Victoria E, Matáix J, Medrano J, Calpena R, Pérez MT, Mañas M (1997). Pancreatic enzyme secretion in response to test meals differing in the quality of dietary fat (olive and sunflower seed oils) in human subjects. Br J Nutr 78: 27–39.
• Yago MD, Martínez-Victoria E, Mañas M, Martínez MA, Matáix J (1997). Plasma peptide YY and pancreatic polypeptide in dogs after long-term adaptation to dietary fats of different degrees of saturation: olive and sunflower oil. J Nutr Biochem 8: 502–507.
• Yadav D, Pitchumoni CS (2003). Issues in hyperlipidemic pancreatitis. J Clin Gastroenterol 36: 54–62.
• Zhuang L, Kim J, Adam RM, Solomon KR, Freeman MR (2005). Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. J Clin Invest 115: 959–968.