Crosstalk between autophagy and DNA repair systems

Crosstalk between autophagy and DNA repair systems

Autophagy and DNA repair are two essential biological mechanisms that maintain cellular homeostasis. Impairment of these mechanisms was associated with several pathologies such as premature aging, neurodegenerative diseases, and cancer. Intrinsic or extrinsic stress stimuli (e.g., reactive oxygen species or ionizing radiation) cause DNA damage. As a biological stress response, autophagy is activated following insults that threaten DNA integrity. Hence, in collaboration with DNA damage repair and response mechanisms, autophagy contributes to the maintenance of genomic stability and integrity. Yet, connections and interactions between these two systems are not fully understood. In this review article, current status of the associations and crosstalk between autophagy and DNA repair systems is documented and discussed.

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Turkish Journal of Biology-Cover
  • ISSN: 1300-0152
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Lipase from new isolate Bacillus cereus ATA179: optimization of production conditions, partial purification, characterization and its potential in the detergent industry

Elif DEMİRKAN, Aynur AYBEY ÇETİNKAYA, Maoulida ABDOU

Elif ELİF DEMİRKAN, Aynur AYBEY ÇETİNKAYA, Maoulida ABDOU

Zeynep DEMİR ÖKSÜZ, Tuğrul DORUK, Nevin YAĞCI, Sedef TUNCA GEDİK

Identification of differentially expressed microRNAs in primary esophageal achalasia by next-generation sequencing

Mahin GHOLIPOUR, Javad MIKAELI, Seyed Javad MOWLA, Mohammad Reza BAKHTIARIZADEH, Marie SAGHAEIAN JAZI, Naeme JAVID, Narges FAZLOLLAHI, Masoud KHOSHNIA, Naser BEHNAMPOUR, Abdolvahab MORADI

Mahin GHOLIPOUR, Javad MIKAELI, Seyed Javad MOWLA, Mohammad Reza BAKHTIARIZADEH, Marie SAGHAEIAN JAZI, Naeme JAVID, Narges FAZLOLLAHI, Masoud KHOSHNIA, Naser BEHNAMPOUR, Abdolvahab MORADI

Dharaniyambigai KUBERAPANDIAN, Victor Arokia DOSS

Polyhydroxyalkanoate accumulation in Streptomyces coelicolor affected by SCO7613 gene region

Nevin YAĞCI, Zeynep DEMİR ÖKSÜZ, Tuğrul DORUK, Sedef TUNCA GEDİK

Ahmet Sinan SARI, Emre DEMİRÇAY, Ahmet ÖZTÜRK, Ayşen TERZİ, Erdal KARAÖZ

Sinem DEMİRBAĞ-SARIKAYA, Hatice ÇAKIR, Devrim GÖZÜAÇIK, Yunus AKKOÇ

Transcriptome profiling of Stevia rebaudiana MS007 revealed genes involved in flower development

Nurul Hidayah SAMSULRIZAL, Khairul Shahyidi KHADZRAN, Tamil Chelvan MEENAKSHI SUNDRAM, Zarina ZAINUDDIN, Siti Hajar Nor SHAARANI, Nur Sabrina Ahmad AZMI, Sarahani HARUN