Determination of Antioxidant and Oxidant Potentials of Thymbra spicata Collected from Duhok-Iraq

In this study, antioxidant, oxidant and oxidative stress index of Thymbra spicata L. collected from Duhok (Iraq) region were determined. The aerial parts of the plant were extracted with ethanol. Rel Assay Diagnostics kits were used for detect TAS, TOS and OSI values. As a result of the studies, it was determined that TAS value of plant extract was determined 8.399±0.102, TOS value was 6.530±0.115 and OSI value was 0.078±0.001. As a result, it was determined that T. spicata has high antioxidant potential and in this context, can be used as a natural resource.

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Aksoy L, Kolay E, Ağılönü Y, Aslan Z, Kargıoğlu M. 2013. Free radical scavenging activity, total phenolic content, total antioxidant status, and total oxidant status of endemic Thermopsis turcica. Saudi journal of biological sciences, 20(3): 235-239.Bayan Y, Genc N, Kusek M, Gul F, Imecik Z. 2017.

Determination of Chemical Compositions, Antifungal, Antibacterial and Antioxidant Activity of Thymbra spicata L. From Turkey. Fresen Environ Bull, 26(12): 7595-7599

Boullata JI, Nace AM. 2000. Safety issues with herbal medicine. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 20(3): 257-269.

Bozok F. 2018. Herbicidal Activity of Nepeta flavida Essential Oil. Journal of Essential Oil Bearing Plants, 21(6): 1687- 1693.

Doğan H, Akyol E, Akgül H, Talas ZS. 2014. Biologic activities of honeybee products obtained from different phytogeographical regions of Turkey. Turkish Journal of Agriculture-Food Science and Technology, 2(6): 273-276.

Erel O. 2004. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clinical biochemistry, 37(4): 277-285.

Erel O. 2005. A new automated colorimetric method for measuring total oxidant status. Clinical biochemistry, 38(12): 1103-1111.

Ertürk Ö, Tanrıkulu Gİ, Yavuz C, Can Z, Çakır HE. 2017. Chemical compositions, antioxidant and antimicrobial activities of the essential oil and extracts of Lamiaceae family (Ocimum basilicum and Thymbra spicata) from Turkey. International Journal of Secondary Metabolite, 4(3, Special Issue 2): 340-348.

Fiacconi M, Hunt CO. 2015. Pollen taphonomy at Shanidar Cave (Kurdish Iraq): an initial evaluation. Review of Palaeobotany and Palynology, 223: 87-93.

Gul S, Ahmed S, Gul H, Shad KF, Zia-Ul-Haq M, Badiu D. 2013. The antioxidant potential of Brassica rapa L. on glutathione peroxidase, superoxide dismutase enzymes and total antioxidant status. Romanian Review of Laboratory Medicine, 21(2): 161-169.

Kam PCA, Liew S. 2002. Traditional Chinese herbal medicine and anaesthesia. Anaesthesia, 57(11): 1083-1089.

Khalil M, Khalifeh H, Baldini F, Salis A, Damonte G, Daher A, Voci A, Vergani L. 2019. Antisteatotic and antioxidant activities of Thymbra spicata L. extracts in hepatic and endothelial cells as in vitro models of non-alcoholic fatty liver disease. Journal of ethnopharmacology, 239: 111919.

Kılıç C, Can Z, Yılmaz A, Yıldız S, Turna H. 2017. Antioxidant properties of some herbal teas (green tea, senna, corn silk, rosemary) brewed at different temperatures. International Journal of Secondary Metabolite, 4(3, Special Issue 1): 142- 148.

Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TPA. 2007. Recent advances in Indian herbal drug research guest editor: Thomas Paul Asir Devasagayam Indian herbs and herbal drugs used for the treatment of diabetes. Journal of clinical biochemistry and nutrition, 40(3): 163-173.

Mohammed FS, Akgul H, Sevindik M, Khaled BMT. 2018. Phenolic content and biological activities of Rhus coriaria var. zebaria. Fresen Environ Bull, 27(8): 5694-5702.

Mohammed FS, Karakaş M, Akgül H, Sevindik M. 2019a. Medicinal Properties of Allium calocephalum Collected from Gara Mountain (Iraq). Fresen Environ Bull, 28(10): 7419- 7426.

Mohammed FS, Pehlivan M, Sevindik M. 2019b. Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq). International Journal of Secondary Metabolite, 6(4): 317-322.

Ondua M, Njoya EM, Abdalla MA, McGaw LJ. 2019. Antiinflammatory and antioxidant properties of leaf extracts of eleven South African medicinal plants used traditionally to treat inflammation. Journal of ethnopharmacology, 234: 27- 35.

Pandey A, Belwal T, Tamta S, Bhatt ID, Rawal RS. 2019. Phenolic compounds, antioxidant capacity and antimutagenic activity in different growth stages of in vitro raised plants of Origanum vulgare L. Molecular biology reports, 46(2): 2231- 2241.

Pehlivan M, Sevindik M. 2018. Antioxidant and antimicrobial activities of Salvia multicaulis. Turkish Journal of Agriculture-Food Science and Technology, 6(5): 628-631.

Pehlivan M, Mohammed FS, Sevindik M, Akgul H. 2018. Antioxidant and oxidant potential of Rosa canina. Eurasian Journal of Forest Science, 6(4): 22-25.

Qader SW, Abdulla MA, Chua LS, Najim N, Zain MM, Hamdan S. 2011. Antioxidant, total phenolic content and cytotoxicity evaluation of selected Malaysian plants. Molecules, 16(4): 3433-3443.

Selamoglu Z, Akgul H, Dogan H. 2016. Environmental effects on biologic activities of pollen samples obtained from different phytogeographical regions in Turkey. Fresen Environ Bull, 25: 2484-2489.

Sevindik M, Akgul H, Pehlivan M, Selamoglu Z. 2017. Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26(7): 4757-4763.

Shyur LF, Tsung JH, Chen JH, Chiu CY, Lo CP. 2005. Antioxidant properties of extracts from medicinal plants popularly used in Taiwan. Int J Appl Sci Eng, 3(3): 195-202.

Townsend CC, Guest E. 1966-1985. Flora of Iraq, Volumes 1-4, 8-9. Ministry of Agriculture and Agrarian Reform and Bentham-Moxon Trust. Baghdad, Iraq.