Öztin Cemile ÖĞÜN, Selmin ÖKESLİ, Atilla EROL, Ahmet TOPAL, Ateş DUMAN

Remifentanil-sevofluran-azotprotoksit anestezisinde propofol ve tiyopenton'un orta ve ileri yaştaki kadınlarda derlenmeye ve erken kognitif fonksiyonlara etkisi

Bu çalışmada, anestezi idamesinde sevofluran-remifentanil-N2O kullanılan, total abdominal histerektomi geçiren orta ve ileri yaşlardaki kadın hastalarda tiyopenton veya propofol indüksiyonunun erken postoperatif kognitif fonksiyonlar ve derlenmeye etkileri araştırıldı. ASA l-III sınıf, 67 kadın hastada (yaş:40-75) anestezi indüksiyonu Grup PR'de (n=31) 2 mg/kg propofol, grup TR'de (n=36) 5 mg/kg tiyopenton ile sağlandı. Kas gevşetici olarak mivakuryum kullanıldı. Tüm gruplarda anestezi idamesi, 0.25 $mu$g/kg/saat remifentanil -0.5 MAC sevofluran -(60:40) N2O:O2 ile sağlandı. KAH, OAB, solunum sayısı ve SpOg kaydedildi. Tüm hastalarda mini-mental test (MMT), Postanestezi Aldrete skorlaması (PAS) uygulandı. Sedasyon düzeylerinin değişim zamanları ve eş zamanlı VAS ile ağrı skorları kaydedildi. Grup PR'de KAH ve OAB indüksiyonda azaldı (p

Remifentanil-sevoflurane-nitrous oxide anaesthesia: The effects of propofol or thiopentone on early cognitive function and recovery in moderate aged and elderly women

In this study, we investigated the cognitive functions and recovery following thiopentone or propofol induction before remifentanil and sevoflurane-nitrous oxide anaesthesia, in patients undergoing total abdominal hysterectomy operations. In 67 ASA I-Ill class women (age:40-76), anaesthesia was induced with 1.5 mg/kg propofol in Group PR (n=31), and 5 mg/kg thiopentone in Group TR (n=36). Mivacurium was used for muscle relaxation. Anaesthesia was maintained with 0.25 $mu$g/kg/h remifentanil, and a mixture of 0.5 MAC sevoflurane-nitrous oxide: oxygen (60:40). Heart rate (HR), mean arterial pressure (MAP), respiratory rate (RR) and SpO2 were recorded. Mini-mental test (MMT), postanaesthesia Aldrete scoring (PAS) pain scores using visual analog scale (VAS) with the changing times of sedation scores using 4 point sedation scale were recorded simultaneousely. In group PR HR and MAP decreased after induction. In both groups MMT scores were lower than their preopertive values and MMT scores were decreased in group TR when compared to group PR postoperatively. (Preoperatively 23.1±3.7 vs 23.3±4.9, postoperatively 17.1±5.7 vs 14.0±6.0) (p

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