Ayla Günlemez, Canan Baydemir, İlkay Er, Ceren Çetin

Olgunlaşmamış trombosit fraksiyonu konjenital pnömoni için erken belirleyici olabilir mi?

Amaç: Konjenital pnömoninin zamanında tanı ve tedavisi önemlidir. Yenibir hematolojik parametre olan olgunlaşmamış trombosit fraksiyonu, ye tişkin hastalarda trombositopeninin seyri hakkında klinik bilgi edinmekyanında inflamatuar aktiviteyi ölçmek için de kullanılmıştır. Bu çalışmada,konjenital pnömoni tanılı geç preterm bebeklerde olgunlaşmamış trom bosit fraksiyonunun bilinen sepsis biyobelirteçleri ile karşılaştırılması vekonjenital pnömoni için belirleyici değerinin araştırması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya alınan geç preterm bebekler, enfeksiyözve enfeksiyöz olmayan solunum sıkıntısına göre kategorize edildi. Do ğumdan sonraki 12–24. (örnek-1) ve 48–72. saatlerde (örnek-2) olgunlaş mamış trombosit fraksiyonu ve biyobelirteçler için kan örnekleri alındı.Olgunlaşmamış trombosit fraksiyonu, Sysmex XN-3000 ile ölçüldü. Kar şılaştırma için tam kan parametreleri, C-reaktif protein ve prokalsitoningibi sepsis biyobelirteçleri kullanıldı. Bulgular: Çalışmaya konjenital pnömoni grubundan 16, geçici takipnegrubundan 14 olmak üzere toplamda 30 tane trombositopenik olmayangeç preterm bebek alındı. Gruplar arasında gebelik haftası, doğum ağırlığıve sezaryen oranları açısından fark yoktu. Konjenital pnömoni grubunda

Can immature platelet fraction be an early predictorfor congenital pneumonia?

Aim: Timely diagnosis and treatment of congenital pneumonia are crucial. A new hematologic parameter, immature platelet fraction, has been used to gather clinical information on the prognosis of thrombocytopenia, as well as to measure inflammatory activity in adult patients. This study aimed to compare immature platelet fraction and sepsis biomarkers in late-preterm infants diagnosed as having congenital pneumonia and to evaluate its predictive value for congenital pneumonia.Material and Methods: Late-preterms were categorized based on infectious vs. non-infectious etiology of respiratory distress. Two sets of blood samples for markers were taken at 12–24 (sample-1) and 48–72 hours (sample-2) after birth. Immature platelet fraction was measured using a Sysmex XN-3000 analyzer.Results: From a total of 30 non-thrombocytopenic late-preterms, 16 were included in the congenital pneumonia group and 14 comprised the transient tachypnea group. The groups were comparable in terms of gestational age, birth weight, and cesarean section rate. The proportion of prolonged membrane rupture was significantly higher in the

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