Halil KESKİN, Fuat LALOĞLU, Hasan KAHVECİ, Zeynep TÜRKYILMAZ, Müge PAYASLI, Başak AKSOY ADAKLI

Hipofiz kanamasına ikincil merkezi diabetes insipidus gelişen çok düşük doğum ağırlıklı erken doğmuş bir bebekte başarılı intranazal desmopresin asetat tedavisi

Merkezi diabetes insipidus polidipsi, poliüri, susuz kalma, huzursuzluk, yetersiz beslenme, yetersiz büyüme ve hipernatremi ile belirgindir. Bu hastalık antidiüretik hormonun yetersizliği sonucu oluşur. Burada yenidoğan döneminde hipofiz kanamasına ikincil merkezi diyabetes insipidus gelişen ve intranazal desmopresin asetat ile tedavi edilen çok düşük doğum ağırlıklı erken doğmuş bir olgu sunuldu. Desmopresin asetatın çok düşük doğum ağırlıklı erken doğmuş bebeklerde de etkin bir tedavi yöntemi olabileceği vurgulandı. (Türk Ped Arfl 2013; 48: 241-3)

A very low birth weight premature infant developing santral diabetes insipidus secondary to pituitary hemorrhage and cured successfully with intranasal desmopressin acetate

Central diabetes insipidus is characterized by polydipsia, polyuria, dehydration, irritability, poor feeding, failure to thrive and hypernatremia. This disease is caused by lack of antidiuretic hormone. Here, a very low birth weight premature infant who developed central diabetes insipidus secondary to pituitary hemorrhage in the newborn period and was treated successfully with intranasal desmopressin acetate was presented. It was emphasized that desmopressin acetate might be an effective method also in the treatment of very low birth weight premature infants. (Turk Arch Ped 2013; 48: 241-3)

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