Bu çalışmada kliniğimizde 1989 1996 yılları arasında Guillain Barre sendromu tanısıyla izlenen 25 olgu retrospektif olarak değerlendirildi Olgular 2 5 15 5 yaşlar arasında olup 16 olgu 64 erkek 9 olgu 36 kız idi Onaltı olguda 64 iki hafta öncesinde geçirilmiş viral bir enfeksiyon hikayesi saptandı Başlangıç bulgularına göre altı olgu 24 grade V on olgu 40 grade IV ve dokuz olgu da 36 grade III olarak değerlendirildi Grade V dört olguya intravenöz immunoglobulin grade V iki olguya ve grade IV dört olguya plazma exchange transfüzyon uygulanırken grade IV altı olguya da prednizolon tedavisi uygulandı Grade III dokuz olguya ise tıbbi tedavi verilmedi Plazma exchange transfüzyon uygulanan olgularda tedavi etkinliği intravenöz immunoglobulin uygulananlarla eşit bulundu Grade V bir olgu sepsisle eksitus olurken bir olguda ciddi hipertansiyon saptandı ve 24 olgu iyileşme sürecinde taburcu edildi Çocukluk çağında Guillain Barre sendromu tedavisinde plazma exchange transfüzyonunun kolay uygulanabilir olması daha ucuz olması ve diğer tedavi yöntemleri kadar etkili olması nedeniyle tercih edilebilir bir tedavi yöntemi olduğunu düşünüyoruz Anahtar kelimeler: Guillain Barre Sendromu Çocuk Plazma Exchange Transfüzyon

In this study twenty five children diagnosed as Guillain Barre syndrome between 1989 1996 have been evaluated retrospectively Children were aged between 2 5 to 15 5 years and sixteen of them 64 were males and nine 36 were females Sixteen of the cases 64 had a history of viral illness before two weeks Six of the patients 24 were grade V ten 40 were grade IV and nine 36 were grade III in respect to the initial features Four of grade V patients received intravenous immunoglobulin Two of grade V and four of grade IV patients had plasma exchange transfusion and six of grade IV patients received prednisolon None of the grade III patients received medical treatment The effectivity of plasma exchange transfusion and intravenous immunoglobulin treatments were similar Hypertension was detected in one case a grade V patients died of sepsis and twenty four patients were discharged as they had improved We conclude that plasma exchange transfusion is an inexpensive effective easily used method which may be preferred in the treatment of Guillain Barre syndrome of childhood Key wods: Guillain Barre Syndrome Child Plasma Exchange Transfusion